From the Research
Hydroxychloroquine sulfate primarily affects vitamin B12, vitamin D, folate, calcium, and magnesium levels in the body. This medication, commonly used for autoimmune conditions like lupus and rheumatoid arthritis, can interfere with nutrient absorption and metabolism through several mechanisms. It may reduce intestinal absorption of vitamin B12 and folate, while also potentially affecting vitamin D metabolism 1. Additionally, hydroxychloroquine can alter calcium and magnesium balance, which may contribute to muscle weakness experienced by some patients.
Some key points to consider:
- Hydroxychloroquine's impact on nutrient levels can lead to symptoms like fatigue, weakness, or tingling sensations.
- Regular monitoring of these nutrient levels is crucial for patients taking hydroxychloroquine long-term, especially if they experience any symptoms.
- A balanced diet rich in these nutrients or appropriate supplementation may be necessary to mitigate the effects of hydroxychloroquine on nutrient levels.
- However, any supplement regimen should be discussed with a healthcare provider to avoid interactions with the medication 2, 3.
- The nutrient depletion typically develops gradually over months of treatment rather than immediately after starting the medication.
It's essential to note that while hydroxychloroquine has been used for various conditions, including COVID-19, its efficacy and safety for this purpose are still being studied and debated 4, 5. As such, patients should only take hydroxychloroquine under the guidance of a healthcare provider and with careful monitoring of their nutrient levels and overall health.