From the Guidelines
The recommended pediatric Benadryl (diphenhydramine) dose is 1 to 2 mg/kg per dose, with a maximum dose of 50 mg, as stated in the most recent and highest quality study 1. This dosage is based on the child's weight and can be administered orally or intravenously.
- For children, the dose can be calculated as 1 to 2 mg/kg per dose, with a maximum dose of 50 mg.
- The medication should be administered every 4-6 hours, not exceeding 5 doses in 24 hours.
- Liquid formulations are often preferred for younger children, while chewable tablets or regular tablets may be suitable for older children.
- It is essential to use the measuring device provided with liquid medication for accuracy.
- Benadryl works by blocking histamine receptors to relieve allergy symptoms like itching, sneezing, and runny nose.
- Side effects may include drowsiness, dry mouth, and dizziness.
- This medication should not be given to children under 2 years without medical supervision, and parents should consult a healthcare provider before administering Benadryl, especially if the child has medical conditions or takes other medications. The American Academy of Pediatrics and other medical organizations recommend this dosage, as seen in the guidelines for managing food allergy 1.
- Always consult a healthcare provider before administering Benadryl to children, especially if they have medical conditions or take other medications.
- It is crucial to monitor the child's response to the medication and adjust the dosage as needed.
From the FDA Drug Label
Directions • take every 4 to 6 hours, or as directed by a physician• do not take more than 6 doses in 24 hours age/dose Adults and children over 12 years of age10 mL (25 mg) to 20 mL (50 mg) Children 6 to under 12 years of age10 mL (25 mg) Children under 6 years of ageDo not use
The recommended pediatric dose of Benadryl (diphenhydramine) is:
- For children 6 to under 12 years of age: 10 mL (25 mg) every 4 to 6 hours, as directed by a physician, not to exceed 6 doses in 24 hours 2
- For children under 6 years of age: Do not use 2
From the Research
Pediatric Benadryl Dose
- The provided studies do not directly address the pediatric Benadryl dose, but they discuss the use of diphenhydramine in various contexts, including its side effects and comparisons with other antihistamines 3, 4, 5, 6, 7.
- Diphenhydramine is known to have many side effects, including sedation and risk of toxicity in overdose, which may be particularly concerning in pediatric populations 3.
- The studies suggest that second-generation antihistamines may be a better option than diphenhydramine due to their fewer side effects and similar efficacy 3, 7.
- However, there is no specific information provided on the recommended dose of Benadryl for pediatric use, and it is essential to consult a healthcare professional for guidance on this matter.
- The available studies focus on the pharmacokinetics, efficacy, and safety of diphenhydramine in adults or do not provide specific dosing recommendations for children 4, 5, 6.