What are the causes of delayed gastric emptying (gastroparesis)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 8, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Stomach Not Processing Food Symptom

  • Single Most Likely Diagnosis
    • Gastroesophageal reflux disease (GERD): This condition is characterized by the stomach's inability to properly process food, leading to symptoms like heartburn, bloating, and discomfort. The high prevalence of GERD in the population and its common presentation with digestive symptoms make it a likely diagnosis.
  • Other Likely Diagnoses
    • Gastroparesis: A condition where the stomach takes too long to empty its contents, leading to nausea, vomiting, and feeling full after eating only a small amount of food. This diagnosis is likely due to its direct impact on stomach function and food processing.
    • Peptic ulcer disease: Ulcers in the stomach or duodenum can cause pain, bloating, and discomfort, leading to the sensation that the stomach is not processing food properly. The presence of ulcers can impede normal digestive processes.
    • Irritable bowel syndrome (IBS): Although primarily affecting the intestines, IBS can cause bloating, abdominal pain, and changes in bowel movements, which might be perceived as the stomach not processing food correctly.
  • Do Not Miss Diagnoses
    • Gastric cancer: Although rare, gastric cancer can present with nonspecific symptoms like difficulty digesting food, weight loss, and abdominal pain. Missing this diagnosis could be fatal, making it crucial to consider, especially in high-risk populations or those with persistent symptoms.
    • Intestinal obstruction: A blockage in the intestines can prevent normal food passage, leading to severe abdominal pain, vomiting, and constipation. This is a medical emergency that requires immediate attention.
    • Inflammatory bowel disease (Crohn's disease or ulcerative colitis): These conditions can cause significant gastrointestinal symptoms, including difficulty processing food, due to inflammation and damage to the digestive tract.
  • Rare Diagnoses
    • Zollinger-Ellison syndrome: A rare disorder characterized by excessive gastric acid production, leading to severe ulcers and digestive issues. Its rarity and specific symptoms make it less likely but still a consideration in complex cases.
    • Eosinophilic gastroenteritis: A rare condition involving eosinophilic infiltration of the gastrointestinal tract, leading to symptoms like abdominal pain, nausea, and difficulty swallowing. Its rarity and specific diagnostic criteria place it in the category of rare diagnoses.
    • Chronic mesenteric ischemia: A condition where the intestines do not receive enough blood flow, leading to abdominal pain after eating and difficulty digesting food. This diagnosis is rare and typically considered in patients with significant vascular disease.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.