What are the causes of hemoptysis (coughing up blood)?

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Differential Diagnosis for Hemoptysis

  • Single most likely diagnosis
    • Bronchitis: This is often the most common cause of hemoptysis, especially in smokers or those with a history of respiratory infections. The inflammation and irritation of the bronchial tubes can lead to bleeding.
  • Other Likely diagnoses
    • Pneumonia: Bacterial, viral, or fungal pneumonia can cause hemoptysis due to the infection and inflammation of the lung tissue.
    • Chronic obstructive pulmonary disease (COPD): COPD can cause hemoptysis due to the chronic inflammation and damage to the lung tissue.
    • Lung cancer: Although less common, lung cancer can cause hemoptysis, especially in smokers or those with a history of exposure to carcinogens.
    • Pulmonary embolism: A pulmonary embolism can cause hemoptysis, especially if it is large and causes infarction of the lung tissue.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary artery aneurysm or pseudoaneurysm: These are rare but potentially life-threatening conditions that can cause massive hemoptysis.
    • Tuberculosis: Although less common in some areas, tuberculosis can cause hemoptysis and is important to consider, especially in high-risk populations.
    • Goodpasture's syndrome: This is a rare autoimmune disease that can cause hemoptysis and renal failure.
    • Mitral stenosis: This is a heart condition that can cause hemoptysis due to the increased pressure in the pulmonary veins.
  • Rare diagnoses
    • Bronchiectasis: This is a condition characterized by the dilation of the bronchial tubes, which can cause hemoptysis.
    • Cystic fibrosis: This is a genetic disorder that can cause hemoptysis due to the chronic inflammation and damage to the lung tissue.
    • Arteriovenous malformation (AVM): This is a rare condition where there is an abnormal connection between the arteries and veins, which can cause hemoptysis.
    • Vasculitis: This is a group of conditions that cause inflammation of the blood vessels, which can cause hemoptysis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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