From the Guidelines
Mylanta (Aluminum Hydroxide and Magnesium Hydroxide) is not recommended as a first-line treatment for chronic idiopathic constipation, but rather for its antacid properties to neutralize stomach acid and relieve heartburn, indigestion, and upset stomach. The use of magnesium hydroxide, a component of Mylanta, has been studied in the context of chronic idiopathic constipation (CIC), and according to the american gastroenterological association-american college of gastroenterology clinical practice guideline 1, magnesium oxide (MgO) dosing of 1.5 g/d has been evaluated in RCTs and shown to exert a beneficial effect on constipation-related symptoms. However, the guideline also notes that lower MgO doses of 500 mg/d to 1 g/d are often used in clinical practice, and the bioavailability and clinical efficacy of other formulations of magnesium, including magnesium hydroxide, are unknown. Some key points to consider when using Mylanta include:
- The standard adult dose is 2-4 teaspoons (10-20 mL) taken orally as needed, up to 4 times per day
- Mylanta works by neutralizing stomach acid and coating the esophagus and stomach lining
- Its active ingredients are aluminum hydroxide, magnesium hydroxide, and simethicone
- Do not exceed the recommended dose or use for more than 2 weeks without consulting a doctor
- If you're pregnant, breastfeeding, or have kidney problems, consult your healthcare provider before use
- Side effects are generally mild but may include constipation or diarrhea It's essential to note that while Mylanta may provide relief for heartburn, indigestion, and upset stomach, its use should be guided by the potential risks and benefits, particularly in patients with kidney problems, as hypermagnesemia is more likely to occur in individuals with significant renal impairment 1.
From the Research
Uses of Mylanta (Aluminum Hydroxide and Magnesium Hydroxide)
- Mylanta is used to neutralize stomach acid and relieve heartburn, indigestion, and upset stomach 2, 3.
- It is commonly used to treat symptoms of gastroesophageal reflux disease (GERD), such as acid reflux and esophagitis 4, 5.
- Mylanta can also be used to treat stress gastritis, non-ulcer dyspepsia, and minor episodes of heartburn 2.
- Additionally, it can be used as an antacid to neutralize acid in the esophagus, although it does not significantly affect gastric pH or prevent subsequent heartburn episodes 6.
Mechanism of Action
- Mylanta works by partially neutralizing gastric hydrochloric acid and inhibiting the proteolytic enzyme, pepsin 2.
- The aluminum and magnesium salts in Mylanta have their own pharmacological characteristics, which are important for determining the appropriate use of the product 2.
Comparison to Other Treatments
- Mylanta has been compared to other treatments, such as cimetidine and proton pump inhibitors, in the treatment of gastric ulcers and GERD 4, 5, 3.
- While Mylanta can provide symptomatic relief, it may not be as effective as other treatments, such as proton pump inhibitors, in healing ulcers or controlling gastric acid production 4, 5, 6, 3.