Does Kussmaul's sign occur with cardiac tamponade?

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From the Guidelines

Kussmaul's sign can occur with cardiac tamponade, but it is not a typical finding and is more commonly associated with constrictive pericarditis or effusive-constrictive disease. Kussmaul's sign is characterized by a paradoxical increase in jugular venous pressure (JVP) during inspiration, rather than the normal decrease. In cardiac tamponade, fluid accumulates in the pericardial space, creating pressure that restricts cardiac filling. However, the presence of Kussmaul's sign in cardiac tamponade is less common and may indicate a transition to effusive-constrictive disease, as noted in the 2004 European Society of Cardiology guidelines 1. The 2015 ESC guidelines for the diagnosis and management of pericardial diseases also mention that Kussmaul's sign is not a typical finding in cardiac tamponade, but rather in constrictive pericarditis or effusive-constrictive disease 1.

Some key points to consider in the diagnosis of cardiac tamponade include:

  • Clinical presentation: hypotension, pulsus paradoxus, raised jugular venous pressure, muffled heart sounds, and tachycardia
  • Echocardiography: pericardial effusion, diastolic collapse of the right ventricle, and abnormal ventricular septal motion
  • Cardiac catheterization: equilibration of average diastolic pressure and characteristic respiratory reciprocation of cardiac pressures

In terms of treatment, the 2015 ESC guidelines recommend drainage of the pericardial fluid, preferably by needle pericardiocentesis, with the use of echocardiographic or fluoroscopic guidance, and should be performed without delay in unstable patients 1.

It is essential to note that the presence of Kussmaul's sign in cardiac tamponade may indicate a more complex clinical scenario, and the diagnosis and treatment should be guided by a comprehensive evaluation of the patient's clinical presentation, imaging studies, and hemodynamic parameters.

From the Research

Kussmaul's Sign and Cardiac Tamponade

  • Kussmaul's sign is not explicitly mentioned in the provided studies as a characteristic of cardiac tamponade 2, 3, 4, 5, 6.
  • Cardiac tamponade is characterized by hypotension, increased jugular venous pressure, and distant heart sounds (Beck triad) 2.
  • Other clinical findings in patients with cardiac tamponade include dyspnoea, orthopnoea, weakness, fatigue, tachycardia, and oliguria 2.
  • Pulsus paradoxus is a key feature of cardiac tamponade, which is a decrease in systolic blood pressure of more than 10 mmHg during inspiration 3, 4.
  • Kussmaul's sign, which is an increase in jugular venous distension during inspiration, is typically associated with constrictive pericarditis, not cardiac tamponade.
  • The diagnosis of cardiac tamponade is primarily based on clinical presentation and echocardiography 2, 3, 4, 5, 6.
  • Treatment of cardiac tamponade involves pericardiocentesis, which can be guided by echocardiography or fluoroscopy 2, 3, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Cardiac tamponade.

Nature reviews. Disease primers, 2023

Research

Cardiac tamponade: an educational review.

European heart journal. Acute cardiovascular care, 2021

Research

Cardiac tamponade.

Current opinion in critical care, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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