How to evaluate diplopia (double vision)?

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Last updated: May 22, 2025View editorial policy

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From the Guidelines

To evaluate double vision, start by determining if it's monocular or binocular, and then perform a complete neurological examination, including eye movement testing, pupillary responses, and visual field assessment, as recommended by the most recent study 1. When evaluating double vision, it is essential to consider the patient's medical history, including any previous strabismus surgery or chronic conditions that may be contributing to the diplopia.

  • A description of ocular misalignment, including the angle and direction of the strabismus, is crucial in determining the underlying cause of the double vision 1.
  • The presence of treatable causes of vision loss should be determined prior to strabismus surgery and treated as possible or appropriate, as suggested by 1.
  • A complete sensorimotor examination should be performed, and misalignment should be measured by prism and alternate cover test, if possible, as recommended by 1.
  • Consider urgent neuroimaging (MRI or CT) if double vision is sudden, associated with headache, or other neurological symptoms, as this could indicate stroke, aneurysm, or mass lesion, as indicated by 1.
  • Blood tests may be needed to check for myasthenia gravis, thyroid dysfunction, or diabetes, and document the pattern of double vision in different gaze directions, as specific patterns can point to particular nerve palsies, as suggested by 1.
  • Temporary management includes patching one eye or using prism glasses while awaiting definitive treatment of the underlying cause, and double vision evaluation is critical because it may represent serious neurological conditions requiring prompt intervention, as emphasized by 1.

From the Research

Evaluation of Double Vision

To evaluate double vision, a systematic approach to the history and physical examination is required 2. The following steps can be taken:

  • Take a comprehensive history to delineate the exact type of visual disturbance experienced by the patient 3
  • Examine the patient to pinpoint the aetiology, which is crucial for further management 3
  • Determine if the diplopia is monocular or binocular in origin, as this can help guide the diagnosis 2, 4
  • Use simple clinical tests to detect ocular misalignment or strabismus, which can cause binocular diplopia 4
  • Consider urgent imaging for patients with acute onset diplopia, especially if accompanied by headache or pupillary involvement 4

Causes of Double Vision

Double vision can have various causes, ranging from benign to sight or life threatening if left untreated 3. Some common causes include:

  • Ocular misalignment or strabismus 4
  • Neurologic causes, such as cranial nerve palsy 5
  • Extraocular muscle disorders 2
  • Microvascular causes, which often spontaneously resolve within six months 4

Diagnostic Approach

A logical, localization-driven, and evidence-based approach is the most effective way to arrive at the correct diagnosis and provide the best outcome for the patient 5. This approach includes:

  • Developing a differential diagnosis based on the patient's history and examination findings 5
  • Using confirmatory examination techniques to support the diagnosis 5
  • Determining an appropriate diagnostic strategy, which may include imaging or other tests 5, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Pearls: diplopia.

Seminars in neurology, 2010

Research

What you need to know about assessing a patient with diplopia.

British journal of hospital medicine (London, England : 2005), 2023

Research

Diplopia: Diagnosis and management.

Clinical medicine (London, England), 2022

Research

Approach to Diplopia.

Continuum (Minneapolis, Minn.), 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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