What is the pitfall of the Beers (Explicit Criteria for Determining Potentially Inappropriate Medication Use in the Elderly) criteria?

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Last updated: May 22, 2025View editorial policy

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From the Guidelines

The main pitfall of the Beers Criteria is its limited applicability across diverse patient populations, failing to account for individual patient circumstances, comorbidities, and risk-benefit assessments, as highlighted in the most recent study by 1. While the Beers Criteria serve as a valuable tool for identifying potentially inappropriate medications for older adults, they should not be used as an absolute contraindication list but rather as a starting point for clinical decision-making. Many medications on the list may be appropriate for certain patients despite their inclusion. For example, amitriptyline appears on the list due to anticholinergic effects, but might still be the best option for some patients with neuropathic pain. Some key points to consider when using the Beers Criteria include:

  • The criteria do not adequately address drug-drug interactions, which are often more problematic than single medications alone, as noted in 1.
  • The Beers Criteria require regular updates as new medications and evidence emerge, meaning clinicians must ensure they're using the most current version, as emphasized in 1.
  • The criteria were developed primarily based on American prescribing patterns and may not fully translate to healthcare systems in other countries with different medication availability and prescribing practices. It is essential to consider these limitations when applying the Beers Criteria in clinical practice to ensure optimal patient care and minimize potential harm. The process of identifying drug therapy problems, as outlined in 1, can help clinicians optimize medication regimens and reduce the risk of adverse events. Ultimately, the Beers Criteria should be used as a guide, rather than a rigid framework, to support informed decision-making and individualized patient care, as supported by the latest evidence from 1.

From the Research

Pitfalls of the Beers Criteria

  • The Beers Criteria may not be applicable to all older adults, particularly those in palliative and hospice care 2, 3.
  • The criteria are based on a modified Delphi method, which may not always provide precise information 4.
  • The application of the Beers Criteria requires careful consideration and thoughtfulness to support, rather than replace, shared clinical decision-making 3.
  • The criteria may not account for individual variations in kidney function and drug-drug interactions, which can affect the appropriateness of medication use in older adults 2.
  • The Beers Criteria are specific to the United States and may not be directly applicable to other countries, where different medications and healthcare systems may be in use 3.
  • The criteria may not address the issue of anticholinergic medication use, which can increase the risk of falls, delirium, and cognitive impairment in older adults 5.
  • The Beers Criteria are updated periodically, but the updates may not always reflect the latest evidence or changes in clinical practice 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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