What is the most likely diagnosis for a 62-year-old woman with radiating right leg pain and a history of polymyositis treated with prednisone and azathioprine?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

  • Single most likely diagnosis
    • D) Herniated lumbar disc: The patient's symptoms of pain radiating down her right leg while walking, occasional moderate pain in her right hip while sitting, and a positive straight-leg raise test are highly suggestive of a herniated lumbar disc. The decreased sensation over the lateral aspect of the right lower extremity also supports this diagnosis.
  • Other Likely diagnoses
    • A) Avascular necrosis of the hip: The patient's long-term use of prednisone increases her risk of avascular necrosis, and her symptoms of hip pain could be consistent with this condition.
    • B) Corticosteroid-induced myopathy: Although the patient's muscle strength is relatively preserved, her long-term use of prednisone puts her at risk for corticosteroid-induced myopathy, which could contribute to her symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • C) Femoral vein occlusion: Although less likely, femoral vein occlusion is a potentially life-threatening condition that could present with leg pain and swelling. It is essential to consider this diagnosis to avoid missing a potentially fatal condition.
    • E) Polymyositis flare: A flare of the patient's underlying polymyositis could potentially cause her symptoms, and it is crucial to consider this diagnosis to ensure that her treatment is adequate.
  • Rare diagnoses
    • Other rare conditions, such as spinal stenosis, spondylolisthesis, or a spinal tumor, could also be considered, but they are less likely given the patient's presentation and history.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.