From the Research
Yes, statins can potentially cause numbness in the lips and tongue, as evidenced by a case study where a patient developed dysesthesias in the tongue and mouth after taking atorvastatin 1. This sensation, known as paresthesia, may occur as part of a broader spectrum of neurological side effects associated with statin medications. The mechanism behind this side effect likely involves the impact of statins on nerve function, possibly through reduction of coenzyme Q10 levels or alterations in cell membrane function. Some studies have reported oral symptoms such as dry mouth, itchiness, bitterness, and cough associated with statin treatment, which improved after temporary interruption of the treatment 2. However, it's essential to note that the benefits of statins in reducing cardiovascular mortality and morbidity outweigh the risks of adverse effects, including neurological side effects 3, 4. If you experience numbness in your lips or tongue while taking a statin, you should contact your healthcare provider promptly rather than discontinuing the medication on your own. Your doctor may recommend reducing the dosage, switching to a different statin, or in some cases, supplementing with CoQ10. It's crucial to balance the cardiovascular benefits of statins against these potential side effects, and your healthcare provider can help determine the best approach for your specific situation, considering the latest guidelines and evidence 4.