From the Guidelines
Nattokinase is not recommended for muscular stiffness due to a lack of evidence supporting its effectiveness for this condition. The provided evidence does not mention nattokinase as a treatment option for muscular stiffness or low back pain, and instead focuses on other medications and therapies such as skeletal muscle relaxants, tricyclic antidepressants, and gabapentin 1.
Key Considerations
- The American College of Physicians and the American Pain Society recommend the use of skeletal muscle relaxants, tricyclic antidepressants, and gabapentin for the treatment of low back pain, but do not mention nattokinase as a treatment option 1.
- Herbal therapies such as devil's claw, willow bark, and capsicum may be safe options for acute exacerbations of chronic low back pain, but their benefits are small to moderate and more research is needed to confirm their effectiveness 1.
- It is essential to consult with a doctor before starting any new supplement or medication, especially if you are on blood thinners or have other health conditions.
Important Factors to Keep in Mind
- The potential benefits and harms of any treatment should be carefully weighed before starting therapy.
- A time-limited course of therapy is recommended for medications such as benzodiazepines, which are associated with risks for abuse, addiction, and tolerance 1.
- Lifestyle modifications such as proper hydration, stretching, and regular exercise are essential for managing muscular stiffness and should be combined with any treatment approach.
From the Research
Muscular Stiffness and Nattokinase
- There is limited research directly linking nattokinase to the alleviation of muscular stiffness.
- Studies have focused on the thrombolytic, antihypertensive, anti-atherosclerotic, and lipid-lowering effects of nattokinase 2, 3, 4.
- One study discussed the treatment and prevention of exercise-associated muscle cramps, but did not mention nattokinase as a potential treatment option 5.
- Nattokinase has been shown to have anti-inflammatory and anti-oxidative stress effects, which could potentially be beneficial in reducing muscle stiffness, but this has not been directly studied 6.
- Further research is needed to determine the potential benefits of nattokinase in alleviating muscular stiffness.