Can nattokinase help with muscle hypertonia (muscular tightness)?

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Last updated: February 21, 2025View editorial policy

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From the Research

Nattokinase may potentially help with muscular tightness, but evidence is limited and it should not be considered a primary treatment for muscle hypertonia. Nattokinase is an enzyme derived from fermented soybeans, thought to have anti-inflammatory and blood-thinning properties that could theoretically help reduce muscle tension 1. A typical dose is 100-200 mg taken once or twice daily. If you want to try nattokinase for muscle tightness:

  • Choose a reputable supplement brand
  • Start with a low dose and increase gradually
  • Take it on an empty stomach for better absorption
  • Be patient, as effects may take several weeks to notice
  • Consult your doctor first, especially if you take blood thinners The potential muscle-relaxing effects are likely due to improved circulation and reduced inflammation, as suggested by its fibrinolytic, antithrombotic, anti-inflammatory, and antioxidant effects 1. However, more research is needed to confirm its effectiveness specifically for muscle tightness. For muscle tightness, proven methods like stretching, massage, heat therapy, and proper hydration should be prioritized 2. Nattokinase could be considered as a complementary approach, not a replacement for these established techniques. Its safety profile has been established in patients with vascular diseases 3, but its use in muscle hypertonia requires further investigation.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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