What is the most common cause of diarrhea in children under 2 years old in Europe: Escherichia coli (E. coli) or Campylobacter?

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Last updated: May 27, 2025View editorial policy

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From the Research

Rotavirus is the most common cause of diarrhea in children under 2 years old in Europe, not E. coli or Campylobacter, as it is a leading cause of severe gastroenteritis and diarrhea in young children worldwide, including Europe. Actually, rotavirus is a virus rather than a bacteria, but it remains the leading cause of severe gastroenteritis and diarrhea in young children worldwide, including Europe. Before widespread vaccination, rotavirus was responsible for approximately 40% of hospitalizations for diarrhea in young European children. While both E. coli and Campylobacter can cause diarrheal illness in children, they are less common causes in this age group compared to rotavirus, with studies such as 1 showing that Salmonella spp. and diarrheagenic Escherichia coli (DEC) are more commonly detected pathogens in children under 5 years of age, but still less common than rotavirus. Norovirus is the second most common viral cause. The introduction of rotavirus vaccines (Rotarix and RotaTeq) has significantly reduced the burden of rotavirus disease in countries with established vaccination programs, as seen in studies such as 2, which highlights the importance of prevention through immunization rather than focusing solely on treatment of diarrheal diseases in young children.

Some key points to consider:

  • The most common bacterial pathogens causing diarrhea in children under 5 years of age are Salmonella spp., DEC, Campylobacter spp., and Aeromonas spp., as shown in 1.
  • Rotavirus vaccines have significantly reduced the burden of rotavirus disease in countries with established vaccination programs, as seen in 2.
  • Antibiotic resistance is a growing concern in the treatment of bacterial diarrhea, with studies such as 3 showing high resistance rates to certain antibiotics in common bacterial pathogens.
  • Prevention through immunization and improved hygiene practices are crucial in reducing the burden of diarrheal diseases in young children, as highlighted in 4.

It's worth noting that while E. coli and Campylobacter can cause diarrheal illness in children, they are not the most common causes in this age group, and the focus should be on preventing and treating the most common causes, such as rotavirus, as seen in 5.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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