Does Sildenafil (Viagra) cause iron deficiency anemia?

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From the Research

Viagra (sildenafil) does not cause iron deficiency, as there is no established connection between its use and decreased iron levels in the body. The mechanism of action of Viagra, which involves inhibiting the enzyme phosphodiesterase type 5 (PDE5) to increase blood flow to the penis, does not interfere with iron absorption, storage, or red blood cell production 1, 2. Iron deficiency is typically caused by inadequate dietary iron intake, blood loss, or problems with iron absorption in the digestive tract. If symptoms of iron deficiency such as fatigue, weakness, pale skin, or shortness of breath occur while taking Viagra, they are likely unrelated to the medication and should be evaluated separately by a healthcare provider. Common side effects of Viagra include headache, flushing, indigestion, nasal congestion, and visual disturbances, but changes in iron status are not among them 3, 1.

The provided evidence does not support a link between Viagra use and iron deficiency, with studies focusing on the safety and efficacy of Viagra in treating erectile dysfunction 3, 1, 2, and other studies discussing iron deficiency and its treatment with various iron formulations 4, 5. However, these studies do not mention Viagra as a cause of iron deficiency. Therefore, if you are concerned about iron deficiency, it is essential to consult with your doctor for proper testing and treatment, as iron deficiency can have significant effects on morbidity, mortality, and quality of life 4, 5.

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