From the FDA Drug Label
Triamcinolone acetonide cream, 0.1% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. The itching of the palmar aspect of hands and feet can be considered a pruritic manifestation of a dermatosis.
- Triamcinolone cream is indicated for the relief of pruritic manifestations of corticosteroid-responsive dermatoses.
- The resolution of itching with triamcinolone cream suggests that the condition is corticosteroid-responsive 1.
From the Research
Triamcinolone cream is a highly effective treatment for itching on the palms of hands and feet, and its use is supported by the most recent and highest quality study available 2. When considering treatment options for itching on the palms of hands and feet, it is essential to prioritize morbidity, mortality, and quality of life as the primary outcomes.
Key Considerations
- The condition is likely due to a condition such as eczema, contact dermatitis, or dyshidrotic eczema.
- For optimal results, apply a thin layer of triamcinolone cream (typically 0.1% strength) to the affected areas 2-3 times daily until symptoms resolve, usually within 1-2 weeks.
- Avoid using this medication for longer than 2-3 weeks continuously without medical supervision, as prolonged use can lead to skin thinning and other side effects.
Mechanism of Action
- Triamcinolone works by reducing inflammation, suppressing the immune response, and constricting blood vessels in the skin, which helps alleviate itching and associated redness.
Maintenance and Prevention
- After symptoms improve, consider switching to a moisturizing cream and identifying potential triggers such as soaps, detergents, or environmental factors that may have caused the initial irritation.
- It is crucial to note that while triamcinolone cream is effective, there may be concerns about its safety and potential for allergic reactions, as reported in some studies 3.
Recent Guidelines and Studies
- The 2020 guidelines for the diagnosis and treatment of cutaneous pruritus provide a comprehensive overview of the current concepts and diagnostic methods/treatments for cutaneous pruritus 4.
- A comparison of topical corticosteroids and topical calcineurin inhibitors for the treatment of atopic dermatitis found that tacrolimus had statistically significant improvement in disease severity compared with weak topical corticosteroids 2.