What are the differential diagnoses for intermittent testicular pain of non-traumatic origin, also known as passive testicular pain ( orchialgia )?

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Differential Diagnosis for Passive Testicular Pain

Single Most Likely Diagnosis

  • Epididymitis: This is the most common cause of passive testicular pain, often resulting from a bacterial infection, typically Chlamydia or Gonorrhea. The pain is usually gradual in onset and can be accompanied by other symptoms such as swelling, redness, and discharge.

Other Likely Diagnoses

  • Orchitis: Inflammation of one or both testicles, usually caused by viral or bacterial infections. It can present with pain, swelling, and tenderness of the testicles.
  • Testicular torsion (partial or intermittent): Although testicular torsion typically presents with acute, severe pain, partial or intermittent torsion can cause passive pain. It's a condition where the spermatic cord becomes twisted, cutting off the blood supply to the testicle.
  • Varicocele: An enlargement of the veins within the scrotum, similar to varicose veins. It can cause a dull, aching pain, especially after long periods of standing.

Do Not Miss Diagnoses

  • Testicular cancer: Although rare, testicular cancer can present with a painless testicular mass or, less commonly, with pain. Early detection is crucial for effective treatment.
  • Appendicitis (with a retrocecal appendix): In some cases, an inflamed appendix located behind the cecum can irritate the testicle, causing referred pain.
  • Kidney stones: Stones in the urinary tract can cause severe pain, which may radiate to the testicles.

Rare Diagnoses

  • Spermatocele: A cystic structure filled with sperm, which can cause a painless or mildly painful mass but is rarely associated with significant pain.
  • Henoch-Schönlein purpura: A form of vasculitis that can cause testicular pain, along with other symptoms like rash, joint pain, and gastrointestinal issues.
  • Polyarteritis nodosa: A systemic vasculitis that can affect various organs, including the testicles, causing pain and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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