From the FDA Drug Label
The expected symptoms with overdosage are those of excessive beta-adrenergic stimulation and/or occurrence or exaggeration of any of the symptoms listed under ADVERSE REACTIONS, e.g., ... tremor, dry mouth, ... In addition, there were reports of ... dry mouth (< 0.5%).
Dry mouth is a potential side effect of terbutaline, also known as Bricanyl. It can occur as a result of excessive beta-adrenergic stimulation or as an adverse reaction to the medication, with an incidence of less than 0.5% 1 1.
From the Research
Bricanyl (terbutaline) can cause dry mouth as a common side effect, and managing this condition is crucial to prevent oral complications and improve quality of life. This occurs because terbutaline is a beta-2 adrenergic agonist that, while primarily targeting the airways to relieve asthma or COPD symptoms, also affects the salivary glands, reducing saliva production 2. To manage this dry mouth, it is essential to:
- Drink plenty of water throughout the day
- Chew sugar-free gum or suck on sugar-free candies to stimulate saliva flow
- Avoid caffeine and alcohol, which can worsen dryness
- Use alcohol-free mouthwash
- Consider over-the-counter artificial saliva products, which may help alleviate symptoms 3. If dry mouth is severe or persistent, it is crucial to consult a healthcare provider, as they might adjust the dosage or recommend additional treatments 4. It is essential not to stop taking Bricanyl without medical advice, as the respiratory benefits typically outweigh this side effect. The dry mouth usually improves as the body adjusts to the medication over time.
According to a recent study, medication use is a common cause of dry mouth, and pharmacists can play a vital role in managing this condition by conducting medication reviews and providing patient education 2. Another study found that nearly two-thirds of commonly prescribed medications can cause dry mouth, highlighting the need for healthcare providers to be aware of this potential side effect 5.
In terms of treatment strategies, a comprehensive approach that includes good oral hygiene practices, saliva substitutes, and prescription cholinergic agonists can help reduce symptoms and complications associated with dry mouth 6. However, it is essential to note that the risk of dry mouth is greatest for drugs used for urinary incontinence, and future research should focus on developing a risk score for medication-induced dry mouth 4.
Overall, managing dry mouth caused by Bricanyl requires a multifaceted approach that includes lifestyle modifications, oral hygiene practices, and potentially, additional treatments. By prioritizing morbidity, mortality, and quality of life, healthcare providers can help patients mitigate the effects of dry mouth and improve their overall well-being.