From the Guidelines
Diclofenac gel is likely to help with Tietze syndrome symptoms, as topical NSAIDs have been shown to improve symptom relief in musculoskeletal injuries, including those similar to Tietze syndrome. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing inflammation, pain, and swelling when applied topically to the affected area. For Tietze syndrome, which involves painful inflammation of the costal cartilage connecting the ribs to the breastbone, apply a thin layer of diclofenac gel (typically 1% or 2% strength) to the painful chest area 3-4 times daily, gently massaging until absorbed. Most people use it for 7-14 days or as directed by their healthcare provider. The gel works locally by inhibiting prostaglandin production, which mediates pain and inflammation, while causing fewer systemic side effects than oral NSAIDs.
- Key benefits of using diclofenac gel for Tietze syndrome include:
- Reduced pain and inflammation
- Improved symptom relief
- Fewer systemic side effects compared to oral NSAIDs
- According to the study published in the Annals of Internal Medicine 1, moderate-certainty evidence showed that topical NSAIDs improved symptom relief, with an odds ratio of 6.39 [CI, 3.48 to 11.75].
- It is essential to note that results may vary between individuals, and some people with Tietze syndrome may need additional treatments such as rest, heat therapy, or other medications. If symptoms persist beyond 7-10 days of using diclofenac gel, consult a healthcare provider for further evaluation.
From the Research
Tietze's Syndrome and Diclofenac Gel
- Tietze's syndrome is a benign, self-limiting arthropathy characterized by tenderness, pain, and edema involving one of the sternocostal, sternoclavicular, or costochondral joints 2.
- The treatment for Tietze's syndrome is usually conservative, with surgical options considered in resistant cases 2.
Efficacy of Diclofenac Gel
- Topical diclofenac has been shown to be effective in reducing pain and inflammation in acute and chronic musculoskeletal pain, with a clinical success rate of around 60% 3.
- Diclofenac gel has been found to be effective in alleviating pain and reducing erythema, edema, and skin temperature in patients with sunburn 4.
- Topical diclofenac is well-tolerated, with mostly mild and easily resolved local skin irritation, and is associated with fewer side effects than other topical NSAIDs and a lower rate of gastrointestinal complications than oral NSAIDs 5.
Application to Tietze's Syndrome
- While there is no direct evidence on the use of diclofenac gel for Tietze's syndrome, its efficacy in reducing pain and inflammation in other musculoskeletal conditions suggests it may be beneficial for Tietze's syndrome 3, 5.
- Topical NSAIDs, including diclofenac gel, have been found to have a favorable benefit-harm ratio for patients with acute pain from non-low back, musculoskeletal injuries, which may include Tietze's syndrome 6.