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Last updated: June 1, 2025View editorial policy

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Differential Diagnosis for Right Hand/Wrist Pain

Single Most Likely Diagnosis

  • Acute Tendinitis or Tenosynovitis: This condition is likely given the sudden onset of pain, swelling, and redness in the hand and wrist, especially if the patient recently engaged in repetitive activities or experienced a minor injury. The shooting/burning pain description aligns with inflammation of the tendons or their surrounding sheaths.

Other Likely Diagnoses

  • Sprain or Strain: A common injury that could result from overuse or a sudden twist, leading to pain, swelling, and limited mobility in the hand and wrist.
  • Cellulitis: Given the redness and swelling, cellulitis (a bacterial skin infection) is a possibility, especially if there's a history of trauma to the skin or an open wound.
  • Ganglion Cyst: Although less likely to cause acute pain, a ganglion cyst could become inflamed or ruptured, leading to sudden onset of pain and swelling.

Do Not Miss Diagnoses

  • Compartment Syndrome: A medical emergency characterized by increased pressure within a muscle compartment, which could lead to nerve and muscle damage. The severe pain, especially on movement, and swelling are red flags.
  • Infectious Arthritis: Bacterial or fungal infection within the joint, which is a serious condition requiring prompt antibiotic treatment to prevent long-term damage.
  • Osteomyelitis: Bone infection, which could present with pain, swelling, and redness, particularly if there's a history of trauma or immune compromise.

Rare Diagnoses

  • Gout or Pseudogout: Although more commonly affecting the lower extremities, these conditions can cause sudden, severe joint pain and swelling in the hand or wrist, especially in patients with a history of these diseases.
  • Scleroderma or Other Connective Tissue Diseases: Conditions like scleroderma can cause hand and wrist pain, swelling, and limited mobility, but these would typically be part of a broader systemic illness.
  • Neoplastic Processes: Tumors, either benign or malignant, could cause pain and swelling but would be less likely to present acutely without a history of gradual onset or other systemic symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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