From the FDA Drug Label
To reduce the development of drug-resistant bacteria and maintain the effectiveness of neomycin sulfate tablets, USP and other antibacterial drugs, neomycin sulfate tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria The FDA drug label does not answer the question.
From the Research
Neosporin is a safe and effective topical agent for preventing infections in minor skin trauma, and its use is recommended for minor cuts and scrapes. The formulation contains neomycin, polymyxin B, and bacitracin in a petrolatum base, which is active against the most common disease-causing pathogens found in wounds and on the skin 1. To use Neosporin properly, apply a thin layer of the ointment directly to the affected area 1-3 times daily, after thoroughly cleaning the wound with mild soap and water.
Key Considerations
- Cover with a sterile bandage if desired, changing the bandage and reapplying the ointment once daily or whenever the bandage becomes wet or dirty.
- Continue use for up to 7 days; if the wound shows signs of infection (increasing redness, warmth, swelling, pus, or worsening pain) or doesn't improve within a week, seek medical attention.
- Avoid using Neosporin near the eyes, in deep wounds, animal bites, or large areas of damaged skin.
- Some people may develop contact dermatitis from neomycin, so discontinue use if rash or irritation occurs. The combination of neomycin, polymyxin B, and bacitracin in Neosporin has been shown to be synergistic against certain bacterial strains, making it an effective choice for preventing infection in minor wounds 2, 3. However, it is essential to note that neomycin has the lowest safety profile of the drugs in this combination, and some people may develop contact dermatitis or other adverse reactions 4. Overall, the benefits of using Neosporin for minor cuts and scrapes outweigh the risks, and it is a recommended treatment option.