What is the recommended dose of magnesium (Mg) glycinate for sleep?

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Last updated: June 4, 2025View editorial policy

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From the Research

The recommended dose of magnesium glycinate for sleep is typically 200-400 mg taken 1-2 hours before bedtime. This amount provides approximately 30-60 mg of elemental magnesium, which can help promote relaxation and improve sleep quality without causing digestive discomfort. Magnesium glycinate is often preferred over other forms of magnesium supplements for sleep because it has better absorption and is less likely to cause laxative effects. The glycine component also has its own calming properties that may enhance sleep.

Key Considerations

  • Start with a lower dose (200 mg) and gradually increase if needed, as individual responses vary.
  • It's essential to note that magnesium supplements may interact with certain medications, including antibiotics and diuretics, so consult with a healthcare provider before starting, especially if you have kidney disease or take other medications.
  • Results may not be immediate, and consistent use over several weeks may be necessary to experience the full benefits for sleep improvement.

Evidence-Based Recommendations

The most recent and highest quality study on this topic is from 2023, which suggests that magnesium supplementation may have a positive effect on sleep quality, although the evidence is not yet conclusive 1. Another study from 2022 found an association between magnesium intake and better sleep quality, as well as a lower likelihood of short sleep duration 2. However, a 2021 systematic review and meta-analysis found that the quality of literature on this topic is substandard, and more research is needed to make well-informed recommendations 3.

Important Factors to Consider

  • Magnesium glycinate is generally considered safe and well-tolerated, but it's crucial to consult with a healthcare provider before starting supplementation, especially if you have any underlying medical conditions or take medications.
  • Individual responses to magnesium supplementation may vary, so it's essential to monitor your sleep quality and adjust your dosage as needed.
  • A healthy lifestyle, including a balanced diet, regular exercise, and stress management, is also essential for promoting good sleep quality.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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