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Differential Diagnosis for an 18-year-old Female with a Painful Lump on the Right Breast

  • Single most likely diagnosis:
    • Fibroadenoma: This is a common benign breast tumor, especially in young women. The fact that the lump is painful and has been present for 2 months, with the patient noticing an increase in size, aligns with the typical presentation of a fibroadenoma, which can grow and sometimes cause discomfort.
  • Other Likely diagnoses:
    • Breast cyst: These are fluid-filled sacs that can develop in the breast and are common in women of reproductive age. They can be painful and may fluctuate in size.
    • Phyllodes tumor: Although less common than fibroadenomas, phyllodes tumors can occur in young women and may present as a rapidly growing, sometimes painful mass.
    • Infection or abscess: Given the painful nature of the lump, an infectious process such as mastitis or a breast abscess should be considered, especially if there are signs of inflammation like redness, warmth, or fever.
  • Do Not Miss diagnoses:
    • Breast cancer: Although breast cancer is rare in young women, a family history of breast cancer (especially at a young age, like the patient's mother being diagnosed at 35) increases the risk. It's crucial to not miss this diagnosis, despite its lower likelihood.
    • Sarcoma: Extremely rare, but sarcomas can occur in the breast and present as a rapidly growing mass. Given the potential for aggressive behavior, missing this diagnosis could have severe consequences.
  • Rare diagnoses:
    • Granulomatous mastitis: A rare inflammatory condition that can mimic breast cancer or other tumors, presenting with a painful mass.
    • Hamartoma: A benign tumor-like growth that can occur in the breast, although it's much less common than fibroadenomas.
    • Pseudoangiomatous stromal hyperplasia (PASH): A rare benign condition that can form a mass in the breast, more commonly seen in young women.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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