From the FDA Drug Label
Lithium may impair mental and/or physical abilities. Muscular weakness and lack of coordination may be early signs of lithium toxicity Neuromuscular: Tremor, muscle hyperirritability (fasciculations, twitching, clonic movements of whole limbs), ataxia, choreo-athetotic movements, hyperactive deep tendon reflexes
Lithium is not known to increase physical strength or lift. In fact, it may impair physical abilities and cause muscular weakness. Therefore, it is unlikely that lithium would increase lift. 1 1
From the Research
No, lithium does not increase physical strength or lifting capacity. Lithium is a medication primarily prescribed for bipolar disorder and certain mood disorders, not as a performance enhancer. In fact, lithium may actually cause side effects that could negatively impact physical performance, such as fatigue, muscle weakness, tremors, and coordination problems, as noted in various studies 2, 3, 4. The medication works by stabilizing mood through its effects on neurotransmitters and signaling pathways in the brain, not by enhancing muscle function or physical capabilities. Some patients on lithium therapy report feeling physically weaker rather than stronger.
Key Points to Consider
- Lithium's primary use is for treating bipolar disorder and certain mood disorders, with a significant body of evidence supporting its efficacy in these conditions 2, 3, 5.
- The medication's effects on physical performance are generally negative, with potential side effects including fatigue, muscle weakness, and coordination problems 2, 3, 4.
- For individuals seeking to increase physical strength, recommended methods include progressive resistance training, proper nutrition, adequate rest, and potentially consulting with a sports medicine professional.
- Using prescription medications like lithium for non-medical purposes is inappropriate and potentially dangerous.
Recent Findings
A recent study published in 2023 6 discusses the potential benefits of low-dose lithium supplementation, including its effects on musculoskeletal function. However, this study does not provide evidence that lithium increases physical strength or lifting capacity. Instead, it highlights the potential benefits of low-dose lithium on overall health and well-being, particularly in the context of aging and age-related diseases.
Clinical Implications
In clinical practice, lithium should be used judiciously and under close supervision, with careful monitoring of its potential side effects and interactions with other medications. Patients on lithium therapy should be advised to report any changes in their physical condition or overall health, and to discuss any concerns or questions they may have with their healthcare provider. The use of lithium as a performance enhancer is not supported by the evidence and is not recommended.