From the Research
Ammonium lactate is a moderately effective treatment for keratosis pilaris, with the most recent and highest quality study suggesting that lactic acid, a component of ammonium lactate, is one of the most effective and safe treatment options for keratosis pilaris 1. The treatment of keratosis pilaris with ammonium lactate typically involves applying a 12% lotion or cream to affected areas twice daily. Improvement in skin roughness and appearance can be expected to begin within 2-4 weeks of consistent use, with the lactic acid component gently exfoliating the skin and breaking down keratin buildup 2. The ammonium hydroxide component helps maintain the skin's pH balance and enhances penetration, allowing for more effective treatment. Side effects are generally mild and may include temporary stinging, redness, or irritation, particularly on sensitive skin 2. For best results, ammonium lactate should be applied after showering to slightly damp skin, and combined with gentle physical exfoliation 1-2 times weekly. If no improvement occurs after 4-6 weeks of consistent use, consulting a dermatologist for alternative treatments, such as urea cream or light and laser therapies, may be necessary 3, 4. It is essential to note that while ammonium lactate is effective, other treatments like 20% urea cream have shown significant improvement in skin smoothness and texture, and may be considered as alternative options 3. Overall, the use of ammonium lactate for treating keratosis pilaris is supported by clinical trials, and its effectiveness can be enhanced by combining it with other treatments and following a consistent skincare routine. The most recent study on keratosis pilaris treatment options suggests that lactic acid, salicylic acid, and the 1064-nm Nd:YAG laser are the most effective and safe treatment options, making ammonium lactate a viable choice for patients with keratosis pilaris 1.