From the FDA Drug Label
Alcohol consumed 30 minutes prior to sumatriptan ingestion had no effect on the pharmacokinetics of sumatriptan.
The answer is no, alcohol does not interact with sumatriptan, as the pharmacokinetics of sumatriptan were not affected by alcohol consumption 30 minutes prior to ingestion 1.
From the Research
Alcohol does not have a significant interaction with sumatriptan, according to the most recent and highest quality study available 2. However, it's essential to consider the potential effects of combining these substances. Both alcohol and sumatriptan can cause similar side effects, such as dizziness, drowsiness, and impaired coordination, which may be intensified when combined. Some key points to consider:
- Alcohol can trigger or worsen migraines in some people, potentially counteracting the beneficial effects of sumatriptan.
- Both alcohol and sumatriptan can cause blood vessel changes, which may create conflicting effects on the cardiovascular system.
- The pharmacokinetic profile of sumatriptan is not significantly affected by an acute migraine attack, old age, or gender, but care should be taken when administering sumatriptan to patients with liver disease 2. If you're taking sumatriptan for migraine treatment, it's best to wait until your migraine has completely resolved and the medication has cleared from your system (approximately 10-12 hours after your last dose) before considering any alcohol consumption. Always consult with your healthcare provider about specific timing recommendations based on your individual health situation and medication regimen.