What are the signs and symptoms of splenic rupture?

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Last updated: June 23, 2025View editorial policy

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From the Guidelines

Splenic rupture is a medical emergency characterized by bleeding from a damaged spleen, and its signs and symptoms include severe pain in the left upper abdomen, tenderness, abdominal rigidity, and signs of internal bleeding such as low blood pressure, rapid heart rate, and confusion, as reported in the World Journal of Emergency Surgery 1. The most common signs and symptoms of splenic rupture include:

  • Severe pain in the left upper abdomen that may radiate to the left shoulder (Kehr's sign)
  • Tenderness when touching the abdomen
  • Abdominal rigidity or guarding
  • Signs of internal bleeding such as low blood pressure, rapid heart rate, dizziness, lightheadedness, and confusion
  • Nausea, vomiting, and extreme fatigue The severity of symptoms depends on the extent of the rupture and blood loss, and these symptoms typically develop after abdominal trauma, though spontaneous rupture can occur in enlarged spleens, as noted in the guidelines for adult and pediatric patients 1. The pain in the left shoulder occurs because blood irritates the diaphragm, which shares nerve pathways with the shoulder, and anyone experiencing these symptoms, especially after abdominal injury, should seek immediate medical attention as untreated splenic rupture can lead to life-threatening hemorrhage and shock, as emphasized in the management of splenic trauma patients 1. The choice of diagnostic technique at admission must be based on the hemodynamic status of the patient, and CT scan with intravenous contrast is the gold standard in hemodynamically stable or stabilized trauma patients, as recommended by the World Society of Emergency Surgery guidelines 1.

From the Research

Signs and Symptoms of Splenic Rupture

The signs and symptoms of splenic rupture can vary, but some common indicators include:

  • Abdominal pain, which can be severe and may radiate to the left shoulder or back 2, 3, 4, 5
  • Nausea and vomiting 2, 3
  • Fever 2, 4
  • Lethargy 2
  • Respiratory distress 2
  • Hemodynamic instability, such as hypotension or tachycardia 3, 6
  • Clinical features of acute abdomen, such as tenderness or guarding 3
  • Leukocytosis or acute anemia 3

Diagnostic Considerations

Diagnosing splenic rupture can be challenging, but certain diagnostic studies can help, including:

  • Computed tomographic (CT) scan of the abdomen, which can demonstrate well-contained splenic laceration and subcapsular hematoma 3
  • Ultrasonography, which can assist in the diagnosis of non-traumatic splenic rupture 5
  • Peritoneal aspiration of fresh blood, which can confirm the presence of internal bleeding 5

Risk Factors and Etiology

Splenic rupture can occur due to various underlying pathologies, including:

  • Trauma, which is the most common cause of splenic rupture 2, 6
  • Hematological diseases, such as infectious mononucleosis 4
  • Malignancies, such as hairy cell leukemia 5
  • Infectious and inflammatory diseases, such as Plasmodium vivax malaria 5
  • Iatrogenic causes, such as colonoscopy 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Splenic rupture: an unusual complication of colonoscopy.

The American journal of gastroenterology, 1997

Research

Spontaneous rupture of the spleen in patients with infectious mononucleosis.

Canadian journal of surgery. Journal canadien de chirurgie, 1993

Research

Delayed splenic rupture: understanding the threat.

Journal of trauma nursing : the official journal of the Society of Trauma Nurses, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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