From the Research
Creatine supplementation may help decrease blood sugar levels, particularly in individuals with type 2 diabetes, as evidenced by a systematic review of randomized clinical trials 1. The potential benefits of creatine supplementation on blood sugar levels have been explored in various studies, with a focus on its effects on glucose metabolism and insulin sensitivity. Research suggests that creatine can improve glucose tolerance and insulin sensitivity, potentially leading to lower blood sugar levels 2.
Key Findings
- A systematic review and meta-analysis found that creatine supplementation had a beneficial effect on glycemic control in diabetic individuals, although the evidence was not sufficient to confirm its efficacy 3.
- Another study found that creatine supplementation combined with exercise training improved glycemic control in type 2 diabetic patients, with a significant reduction in HbA1c levels 4.
- The typical recommended dosage of creatine monohydrate is 3-5 grams daily, taken consistently, and it is generally considered safe for individuals with diabetes or other metabolic conditions to use under medical supervision 5.
Mechanism of Action
- Creatine likely works by enhancing glucose transport into muscle cells through increased expression of glucose transporters and by improving muscle glycogen storage capacity 2.
- The blood sugar-lowering effect of creatine appears to be more pronounced in individuals with insulin resistance or type 2 diabetes, while the effect may be minimal in those with normal glucose metabolism 1.
Recommendations
- Individuals with diabetes or other metabolic conditions should consult with their healthcare provider before starting creatine supplementation, as it may potentially interact with their existing medications or treatment plans 4.
- Taking creatine with a meal rather than on an empty stomach may be beneficial for those concerned about blood sugar management 5.