From the Guidelines

Diaphoresis, or excessive sweating, is primarily caused by heat, exercise, and dehydration.

Heat and exercise: When the body temperature rises due to heat or exercise, it tries to cool itself down by sweating, which can lead to excessive sweating or diaphoresis 1.
Dehydration: Dehydration can exacerbate the problem of diaphoresis, as the body loses more fluids and electrolytes through sweat, leading to a decrease in plasma volume and an increase in plasma osmolality 1.
Medical conditions: Certain medical conditions, such as heart problems, can also cause diaphoresis, as the body's autonomic nervous system is stimulated, leading to symptoms like pale skin, coolness to touch, nausea, vomiting, and sweating 1.

Environmental conditions: Exercising in hot weather, high humidity, or with inadequate fluid intake can contribute to diaphoresis 1.
Individual factors: Factors like age, sex, body mass index, and certain medications can also influence an individual's susceptibility to diaphoresis 1.

Adequate hydration: Drinking enough fluids before, during, and after exercise can help prevent dehydration and diaphoresis 1.
Acclimatization: Gradually acclimatizing to hot weather or intense exercise can help the body adapt and reduce the risk of diaphoresis 1.
Medical evaluation: If diaphoresis is severe or persistent, it is essential to seek medical evaluation to rule out underlying medical conditions 1.

From the Research

Diaphoresis, or excessive sweating, can be caused by various factors, including:
- Certain medications, such as anti-depressants and anti-psychotics, which can act on the hypothalamus, spinal thermoregulatory centres, and sympathetic ganglia or at the eccrine-neuroeffector junction 2
- Sympathetic nervous system abnormalities, which can lead to excessive sweating in response to heat or emotional stimuli beyond physiologic need 3
- Underlying medical conditions, such as thyrotoxicosis, fevers, and neurologic disorders 4
- Idiopathic factors, which can cause focal hyperhidrosis in otherwise healthy individuals 5

Hyperhidrosis can be classified as either primary or secondary based on its etiology 3
Primary hyperhidrosis is often idiopathic, while secondary hyperhidrosis may be caused by underlying medical conditions or medications 6, 5

The mechanisms that cause excessive sweating can be traced to the sympathetic nervous system, part of the autonomic nervous system 3
The hypothalamic sweat center that controls the palms, axillae, and soles may be distinct in hyperhidrosis individuals 3