What are the benefits of a fish oil mesh (Fatty Acid supplement)?

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Last updated: February 26, 2025View editorial policy

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From the Guidelines

Fish oil supplements, containing omega-3 fatty acids, have been shown to significantly reduce the risk of heart disease and all-cause mortality, with recommended intakes ranging from 0.5 to 1.8 grams per day of EPA and DHA. The benefits of fish oil supplements are well-established, with large-scale epidemiologic studies and randomized controlled trials demonstrating their effectiveness in reducing cardiovascular disease risk [ 1 ]. The American Heart Association recommends consuming at least two servings of fish per week, particularly fatty fish, to reduce the risk of heart disease [ 1 ]. For those who cannot get enough omega-3 fatty acids from their diet, supplements may be recommended, with a dose of 1 gram per day for risk reduction [ 1 ].

Some key benefits of fish oil supplements include:

  • Reducing plasma triglycerides and improving insulin sensitivity [ 1 ]
  • Lowering the risk of heart disease and all-cause mortality [ 1 ]
  • Having beneficial effects on platelet aggregation and thrombogenicity [ 1 ]
  • Being beneficial in subjects with diabetes, particularly in reducing plasma triglyceride levels [ 1 ]

However, it is essential to note that fish oil supplements may increase plasma LDL cholesterol, so monitoring is required [ 1 ]. Additionally, the effects of fish oil supplements on glucose metabolism are not likely to be adverse [ 1 ]. Overall, the benefits of fish oil supplements in reducing cardiovascular disease risk and improving overall health outcomes make them a valuable addition to a healthy lifestyle.

From the FDA Drug Label

The FDA drug label does not answer the question.

From the Research

Benefits of Fish Oil Supplements

The benefits of fish oil supplements, which are rich in omega-3 fatty acids, have been extensively studied. Some of the key benefits include:

  • Reduction in the risk of sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease 2
  • Antiarrhythmic, antithrombotic, and anti-inflammatory effects 2, 3
  • Lowering of triglyceride levels, which can help reduce the risk of heart disease 3, 4, 5
  • Reduction in blood pressure, although this effect is typically seen at higher dosages 2, 3
  • Potential benefits in reducing the risk of coronary artery disease, myocardial infarction, heart failure, arrhythmias, and stroke 6

Mechanisms of Action

The mechanisms by which fish oil supplements exert their benefits are complex and multifaceted. Some of the possible mechanisms include:

  • Prevention of arrhythmias and lowering of heart rate 3
  • Decreasing platelet aggregation and lowering triglyceride levels 3, 5
  • Alteration in membrane fluidity and modulation of cardiac ion channels 6
  • Anti-inflammatory, anti-thrombotic, and anti-arrhythmic effects 2, 3, 6

Recommended Intake

The recommended intake of fish oil supplements varies depending on the individual's health status and goals. Some general guidelines include:

  • 1 g per day of eicosapentaenoic acid plus docosahexaenoic acid for cardioprotection 2
  • 2-4 g per day for reducing elevated triglyceride levels 2, 4
  • 1-2 servings of oily fish per week or daily fish oil supplements (around 1 g of omega-3 polyunsaturated fatty acids per day) for adults 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Omega-3 fatty acids.

American family physician, 2004

Research

The effect of lean fish consumption on triglyceride levels.

The Physician and sportsmedicine, 2009

Research

Omega-3 fatty acids from fish oils and cardiovascular disease.

Molecular and cellular biochemistry, 2004

Research

Fish, Fish Oils and Cardioprotection: Promise or Fish Tale?

International journal of molecular sciences, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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