From the Research
Ashwagandha (Withania somnifera) is unlikely to cause death when taken at recommended doses, but like any substance, it could potentially be fatal in extreme overdose situations. The most recent and highest quality study, published in 2023 1, suggests that ashwagandha can cause liver injury in some individuals, but this is typically not fatal. Standard recommended doses of ashwagandha typically range from 300-600 mg of root extract daily. While ashwagandha is generally considered safe for most adults, it can cause side effects including:
- Digestive upset
- Drowsiness
- Liver problems in some individuals The risk of serious harm increases with:
- Extremely high doses
- Drug interactions
- Certain medical conditions Ashwagandha may interact with medications for:
- Thyroid disorders
- Diabetes
- High blood pressure
- Immunosuppressants
- Sedatives, potentially causing dangerous effects People who are:
- Pregnant
- Have autoimmune diseases
- Thyroid disorders
- Upcoming surgery should avoid ashwagandha The herb contains compounds called withanolides that affect multiple body systems, which explains both its therapeutic effects and potential risks. If you experience unusual symptoms while taking ashwagandha, discontinue use and seek medical attention. It is essential to note that the majority of studies, including those published in 2021 2, 2012 3, and 2020 4, 5, support the safety and efficacy of ashwagandha when used as directed. However, as with any supplement, it is crucial to prioritize caution and monitor for potential adverse effects.