What is the best treatment for intertrigo?

From the Guidelines

The best treatment for intertrigo involves keeping the affected skin folds clean, dry, and separated, and applying topical antifungal creams like clotrimazole 1% or miconazole 2% twice daily for 1-2 weeks, as recommended by the Infectious Diseases Society of America 1. To manage intertrigo, it is essential to:

• Keep the affected area clean and dry
• Apply topical antifungal creams like clotrimazole 1% or miconazole 2% twice daily for 1-2 weeks
• Use absorbent powders or moisture-wicking fabrics to keep the area dry
• Wear loose-fitting clothing to reduce friction and moisture buildup
• Consider using combination products containing both antifungal and steroid medications for more severe cases with inflammation Some key points to consider:
• Intertrigo typically occurs in skin folds, especially in obese and diabetic patients 1
• Topical azoles and polyenes, including clotrimazole, miconazole, and nystatin, are effective in treating intertrigo 1
• Keeping the area dry is crucial in preventing the growth of microorganisms that can exacerbate the condition 1
• More severe cases may require the use of low-potency topical steroids like hydrocortisone 1% or combination products containing both antifungal and steroid medications 1 It is essential to note that while the provided evidence includes guidelines for the treatment of candidiasis and psoriasis, the most relevant and recent studies for intertrigo treatment are from 1 and 1, which provide the basis for the recommended treatment approach.

From the Research

Treatment Options for Intertrigo

The best treatment for intertrigo involves a combination of measures to reduce moisture, friction, and infection. Some key treatment options include:

• Keeping the affected area clean and dry 2, 3, 4
• Using absorptive powders such as cornstarch or barrier creams to minimize moisture and friction 3
• Wearing light, nonconstricting, and absorbent clothing and avoiding wool and synthetic fibers 3
• Avoiding heat, humidity, and excessive physical activity 3
• Treating secondary bacterial and fungal infections with antiseptics, antibiotics, or antifungals, depending on the pathogens 2, 3

Topical Treatments

Topical treatments for intertrigo include:

• Antifungal agents such as nystatin, clotrimazole, ketoconazole, oxiconazole, or econazole for fungal lesions 2
• Antibiotics such as mupirocin or oral penicillin for secondary streptococcal infections 2
• Antimicrobial agents for bacterial superinfections 4
• Paste enriched with miconazole nitrate to prevent or treat intertrigo 5

Prevention and Management

Prevention and management of intertrigo involve:

• Correcting predisposing factors such as obesity and sweating 4
• Investing in skin care and skin fold management protocols to improve patient experience and clinical outcomes 6
• Educating patients about precautions with regard to heat, humidity, and outside activities 3