From the Research
Mupirocin can be used to treat erythrasma, as evidenced by a 2020 study where twice daily topical 2% mupirocin ointment therapy led to the resolution of the infection 1, and a 2017 study that reported nine men with erythrasma were successfully managed with mupirocin 2% ointment monotherapy 2. However, it is crucial to note that the most recent and highest quality study should guide treatment decisions. Erythrasma is a bacterial skin infection caused by Corynebacterium minutissimum that typically affects skin folds. The recommended treatment is either topical clindamycin 1% solution applied twice daily for 2 weeks or oral erythromycin 250mg four times daily for 14 days for more extensive cases, as suggested by a 2002 study 3. Alternatively, topical fusidic acid or miconazole can be effective. Applying hydrocortisone or other topical steroids to erythrasma is counterproductive because steroids suppress the immune response and can create an environment where bacteria thrive, potentially worsening the infection or causing it to spread. For proper management, keep the affected areas clean and dry, as moisture promotes bacterial growth. Some studies suggest other treatment options, such as ozonated olive oil, which was found to be effective in a 2016 pilot trial 4, but more research is needed to confirm its efficacy. If symptoms persist after treatment, consult a healthcare provider for reassessment. Key points to consider in the treatment of erythrasma include:
- The use of topical or oral antibiotics, such as clindamycin, erythromycin, or mupirocin
- Avoiding the use of topical steroids, such as hydrocortisone
- Keeping the affected areas clean and dry
- Considering alternative treatment options, such as ozonated olive oil, although more research is needed to confirm their efficacy.