Is it necessary to discontinue Mounjaro (tirzepatide) prior to cataract surgery?

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Last updated: February 28, 2025View editorial policy

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From the Research

It is generally recommended to temporarily pause Mounjaro (tirzepatide) 24-48 hours before cataract surgery and resume it after normal eating is resumed post-procedure to minimize the risk of anesthesia complications. This precaution is taken due to the effects of GLP-1 receptor agonists like Mounjaro on gastric emptying, which could increase the risk of nausea, vomiting, and potential aspiration during anesthesia 1. The decision to pause Mounjaro should be made in consultation with both the surgeon and the doctor who prescribed the medication, taking into account individual factors such as diabetes control, overall health, and the specific surgical approach. It is essential not to stop any medication without explicit medical guidance, as uncontrolled blood sugar could also pose risks during surgery.

Considerations for Cataract Surgery

  • The type of anesthesia used (local or general) may influence the recommendation for pausing Mounjaro
  • The patient's overall health and diabetes control should be considered when making the decision
  • The surgeon may have a different protocol based on their experience and the specific surgical approach

Importance of Medical Guidance

  • Do not stop Mounjaro without consulting both the surgeon and the prescribing doctor
  • Uncontrolled blood sugar can pose risks during surgery, so medical guidance is crucial
  • The decision to pause Mounjaro should be based on individual patient factors and the latest medical evidence 2.

Latest Medical Evidence

  • Recent studies have demonstrated the safety and efficacy of various treatment modalities in patients with diabetic retinopathy who underwent cataract surgery 2
  • However, the specific recommendation for pausing Mounjaro before cataract surgery is based on the most recent and highest quality study available, which emphasizes the importance of individualized medical guidance 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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