What is the treatment for acute bronchitis?

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Treatment of Acute Bronchitis

Antibiotics should not be prescribed for acute bronchitis unless pneumonia is suspected or there is confirmed pertussis infection. 1

Diagnosis and Assessment

Before initiating treatment, it's essential to distinguish acute bronchitis from other conditions:

  • Acute bronchitis is a self-limited inflammation of the large airways characterized by cough with or without phlegm production lasting up to 3 weeks
  • Rule out pneumonia, which is unlikely in the absence of:
    • Tachycardia (heart rate >100 beats/min)
    • Tachypnea (respiratory rate >24 breaths/min)
    • Fever (oral temperature >38°C)
    • Abnormal chest examination findings (rales, egophony, or tactile fremitus) 1

Treatment Algorithm

First-line: Symptomatic Treatment

  1. Cough suppressants:

    • Dextromethorphan or codeine can be offered for short-term symptomatic relief 1
    • Most useful for disruptive cough, especially at night
  2. Other symptomatic treatments that may provide relief:

    • Expectorants (guaifenesin)
    • First-generation antihistamines (diphenhydramine)
    • Decongestants (phenylephrine) 1

Bronchodilators

  • Not recommended for routine use in uncomplicated acute bronchitis 1
  • May be considered only in select patients with wheezing accompanying the cough 1
  • β-agonists have not shown benefit for patients without asthma or COPD 1

Antibiotics

  • Do not prescribe antibiotics for uncomplicated acute bronchitis 1
  • Despite evidence against their use, 65-80% of patients with acute bronchitis receive antibiotics 1
  • Exception: Confirmed or suspected pertussis (whooping cough)
    • Treat with a macrolide antibiotic (erythromycin) or trimethoprim/sulfamethoxazole if macrolides cannot be used
    • Isolate patient for 5 days from start of treatment 1

Patient Communication

When not prescribing antibiotics:

  • Explain that acute bronchitis is primarily viral (>90% of cases) 1
  • Clarify that purulent sputum (green or yellow) does not indicate bacterial infection 1
  • Discuss potential harms of unnecessary antibiotics:
    • Adverse effects (increased risk compared to placebo) 1
    • Contribution to antibiotic resistance 1
  • Set expectations about the natural course of illness (up to 3 weeks) 1

Common Pitfalls to Avoid

  1. Misdiagnosing pneumonia as bronchitis: Always assess for signs of pneumonia using the clinical criteria mentioned above

  2. Prescribing antibiotics based on patient expectation: Many patients expect antibiotics based on previous experiences; take time to explain why they aren't needed 1

  3. Misinterpreting sputum color: Yellow or green sputum is due to inflammatory cells, not bacterial infection 1

  4. Overlooking pertussis: Consider pertussis in patients with prolonged paroxysmal cough, especially during known community outbreaks 1

  5. Overusing bronchodilators: These medications don't benefit most patients with acute bronchitis and may cause side effects like tremor and nervousness 1

Remember that acute bronchitis is self-limiting, and treatment should focus on symptom relief while avoiding unnecessary antibiotics that contribute to antibiotic resistance and potential adverse effects.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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