Treatment of Acute Bronchitis
Antibiotics should not be prescribed for acute bronchitis unless pneumonia is suspected or there is confirmed pertussis infection. 1
Diagnosis and Assessment
Before initiating treatment, it's essential to distinguish acute bronchitis from other conditions:
- Acute bronchitis is a self-limited inflammation of the large airways characterized by cough with or without phlegm production lasting up to 3 weeks
- Rule out pneumonia, which is unlikely in the absence of:
- Tachycardia (heart rate >100 beats/min)
- Tachypnea (respiratory rate >24 breaths/min)
- Fever (oral temperature >38°C)
- Abnormal chest examination findings (rales, egophony, or tactile fremitus) 1
Treatment Algorithm
First-line: Symptomatic Treatment
Cough suppressants:
- Dextromethorphan or codeine can be offered for short-term symptomatic relief 1
- Most useful for disruptive cough, especially at night
Other symptomatic treatments that may provide relief:
- Expectorants (guaifenesin)
- First-generation antihistamines (diphenhydramine)
- Decongestants (phenylephrine) 1
Bronchodilators
- Not recommended for routine use in uncomplicated acute bronchitis 1
- May be considered only in select patients with wheezing accompanying the cough 1
- β-agonists have not shown benefit for patients without asthma or COPD 1
Antibiotics
- Do not prescribe antibiotics for uncomplicated acute bronchitis 1
- Despite evidence against their use, 65-80% of patients with acute bronchitis receive antibiotics 1
- Exception: Confirmed or suspected pertussis (whooping cough)
- Treat with a macrolide antibiotic (erythromycin) or trimethoprim/sulfamethoxazole if macrolides cannot be used
- Isolate patient for 5 days from start of treatment 1
Patient Communication
When not prescribing antibiotics:
- Explain that acute bronchitis is primarily viral (>90% of cases) 1
- Clarify that purulent sputum (green or yellow) does not indicate bacterial infection 1
- Discuss potential harms of unnecessary antibiotics:
- Set expectations about the natural course of illness (up to 3 weeks) 1
Common Pitfalls to Avoid
Misdiagnosing pneumonia as bronchitis: Always assess for signs of pneumonia using the clinical criteria mentioned above
Prescribing antibiotics based on patient expectation: Many patients expect antibiotics based on previous experiences; take time to explain why they aren't needed 1
Misinterpreting sputum color: Yellow or green sputum is due to inflammatory cells, not bacterial infection 1
Overlooking pertussis: Consider pertussis in patients with prolonged paroxysmal cough, especially during known community outbreaks 1
Overusing bronchodilators: These medications don't benefit most patients with acute bronchitis and may cause side effects like tremor and nervousness 1
Remember that acute bronchitis is self-limiting, and treatment should focus on symptom relief while avoiding unnecessary antibiotics that contribute to antibiotic resistance and potential adverse effects.