Apretude (Cabotegravir) Storage Requirements
Apretude (cabotegravir) extended-release injectable suspension should be stored according to the package instructions, which typically indicate room temperature storage after opening.
Storage Requirements Based on Evidence
The storage of medications at appropriate temperatures is crucial for maintaining their efficacy and safety. For Apretude (cabotegravir):
- Cabotegravir extended-release injectable suspension is a long-acting injectable medication for HIV-1 pre-exposure prophylaxis (PrEP) 1
- While the evidence provided doesn't specifically mention Apretude's storage requirements, pharmaceutical guidelines indicate that medications should be stored according to manufacturer instructions on the package
General Medication Storage Principles
Room Temperature Storage
- The United States Pharmacopeia (USP) defines controlled room temperature as between 15°C and 30°C (59°F to 86°F) 2, 3
- When a medication package indicates "room temperature" storage, this typically refers to this USP-defined range
- If room temperatures exceed 30°C (86°F), medications requiring room temperature storage should be moved to a refrigerator 4
Refrigerated vs. Room Temperature Medications
- Some medications must be stored in refrigerators at 2-8°C (ideally 5°C) to maintain efficacy 5
- Others are specifically designed for room temperature storage
- Following the specific storage instructions on the package is critical for maintaining drug stability
Important Considerations
- Always check the specific storage instructions on the medication package or insert
- Medications should not be exposed to direct heat, light, or excessive agitation 4
- If the package indicates room temperature storage, do not refrigerate unless specifically instructed to do so
- After initial use, many medications have specific storage requirements that may differ from unopened product storage 4
Practical Application
- Store Apretude at the temperature indicated on the package
- If the package says room temperature, maintain storage between 15-30°C (59-86°F)
- Allow refrigerated medications to warm to room temperature before administration if indicated 4
- Avoid temperature extremes that can compromise medication integrity
Following the storage instructions provided on the medication package is essential for ensuring the efficacy and safety of Apretude (cabotegravir) extended-release injectable suspension.