Treatment for Patellofemoral Pain Syndrome
Knee-targeted exercise therapy combined with education should be the primary intervention for patellofemoral pain syndrome, with additional supporting interventions tailored to the patient's specific needs. 1
Primary Treatment Approach
Exercise Therapy
Knee-targeted exercises: High certainty evidence supports quadriceps strengthening as the foundation of treatment 1
- Progressive loading of quadriceps in both open and closed chain exercises
- Adjust exercise prescription based on pain severity and irritability
Hip-and-knee-targeted exercises: Consider adding hip exercises, particularly for patients with poor tolerance to loaded knee flexion 1
- Hip strengthening can improve outcomes when combined with knee exercises
- Moderate certainty evidence supports this combined approach
Education
Education should underpin all interventions and be adjusted to the patient's needs 1:
- Challenge inaccurate beliefs about the condition
- Build confidence in understanding the diagnosis
- Explain that pain doesn't necessarily correlate with damage
- Develop insight into recovery timeframes
- Guide load management
- Promote autonomy and reduce fear
Supporting Interventions
Based on thorough assessment findings, consider these additional interventions:
Prefabricated foot orthoses 1
- Prescribe to patients who respond favorably to treatment direction tests
- Customize for comfort by modifying density and geometry
- Most beneficial in the short term
Lower quadrant manual therapy 1
- Moderate certainty evidence supports this for improving function
- Can be used to address specific impairments identified during assessment
Movement/running retraining 1
- Consider for patients whose symptoms align with specific movement pattern issues
- Examples include increasing cadence or step width for runners
Taping 1
- Consider when rehabilitation is hindered by high symptom severity
- Can provide short-term relief to facilitate exercise progression
Assessment Framework to Guide Treatment Selection
When evaluating patients with patellofemoral pain, focus on:
Understanding patient background:
- Population factors (e.g., in-season athlete)
- Impact of symptoms on daily life and activities
- Symptom history and pattern
- Patient goals
Objective evaluation of physical impairments:
- Muscle strength (hip and knee)
- Movement patterns of the lower extremity
- Tissue tolerance to load
- Patellofemoral joint structure/function
- Contextual factors (e.g., fear avoidance)
Common Pitfalls to Avoid
Overreliance on passive treatments: While supporting interventions like taping or orthoses can be helpful, they should complement rather than replace active exercise therapy 1
Ignoring education: Education is not just an add-on but a fundamental component that should be integrated into all aspects of treatment 1
Failing to reassess: If favorable outcomes are not observed after a reasonable period, revisit assessment findings and adjust the intervention approach 1
Overlooking multifactorial etiology: Patellofemoral pain often results from an imbalance of forces acting on the joint due to multiple factors including overuse, quadriceps weakness, and soft-tissue tightness 2
Treatment Algorithm
- Start with knee-targeted exercise therapy and education for all patients
- Assess for specific impairments that might benefit from additional interventions
- Add hip exercises if indicated by assessment findings
- Consider supporting interventions (orthoses, taping, manual therapy, movement retraining) based on individual presentation
- Reassess regularly and adjust treatment approach as needed
The evidence strongly supports this approach, with a best practice guide based on synthesis of high-quality randomized controlled trials, patient perspectives, and expert clinical reasoning 1.