Management of Bronchitis
Antibiotics should not be prescribed for acute uncomplicated bronchitis as it is primarily caused by viruses (>90% of cases) and antibiotics do not improve outcomes while increasing the risk of adverse effects. 1
Differentiating Types of Bronchitis
Acute Uncomplicated Bronchitis
- Self-limited inflammation of large airways with cough lasting up to 6 weeks
- May be productive or non-productive cough
- Often accompanied by mild constitutional symptoms
- Primarily viral in origin (>90% of cases)
Chronic Bronchitis
- Defined as cough and sputum expectoration occurring on most days for at least 3 months of the year and for at least 2 consecutive years 1
- Caused by interaction between inhaled irritants (cigarette smoke, pollutants) and host factors
- May progress to COPD with airflow limitation
Diagnostic Approach
For Acute Bronchitis:
- Rule out pneumonia - pneumonia is unlikely in the absence of all of the following: 1
- Tachycardia (heart rate >100 beats/min)
- Tachypnea (respiratory rate >24 breaths/min)
- Fever (oral temperature >38°C)
- Abnormal chest examination findings (rales, egophony, tactile fremitus)
- Note: Purulent sputum (green or yellow) does NOT indicate bacterial infection 1
For Chronic Bronchitis:
- Evaluate for exposures to respiratory irritants (cigarette smoke, passive smoke, workplace hazards) 1
- Consider pulmonary function testing to assess airflow limitation
Management Plan
1. Acute Uncomplicated Bronchitis
First-line approach:
- No antibiotics (Grade A recommendation) 1
- Refer to the condition as a "chest cold" rather than bronchitis when discussing with patients 1
- Provide realistic expectations for cough duration (typically 10-14 days after office visit) 1
Symptomatic relief options:
- Cough suppressants: dextromethorphan or codeine for short-term symptomatic relief 1
- First-generation antihistamines (diphenhydramine)
- Decongestants (phenylephrine)
- Expectorants (guaifenesin) - though evidence for effectiveness is limited 1
- Vaporized air treatments in low-humidity environments 1
- Elimination of environmental cough triggers (dust, dander) 1
Important caveats:
- β-agonists (albuterol) have not shown benefit for patients without asthma or COPD 1
- Symptomatic therapy has not been shown to shorten illness duration 1
- Over-the-counter treatments may cause minor adverse effects (nausea, vomiting, headache, drowsiness) 1
2. Chronic Bronchitis
First-line approach:
- Avoidance of respiratory irritants (tobacco smoke, workplace hazards) - most effective intervention with 90% of patients having resolution of cough after smoking cessation 1
Pharmacologic therapy for stable chronic bronchitis:
- Short-acting β-agonists to control bronchospasm and dyspnea (Grade A recommendation) 1
- Ipratropium bromide to improve cough (Grade A recommendation) 1
- Long-acting β-agonist combined with inhaled corticosteroid (ICS) for cough control (Grade A recommendation) 1
- For patients with FEV1 <50% predicted or frequent exacerbations: ICS therapy (Grade A recommendation) 1
- Theophylline may be considered for cough control with careful monitoring for complications (Grade A recommendation) 1
- Central cough suppressants (codeine, dextromethorphan) for short-term symptomatic relief (Grade B recommendation) 1
NOT recommended for stable chronic bronchitis:
- Long-term prophylactic antibiotics (Grade I recommendation) 1
- Oral corticosteroids (Grade E/D recommendation) 1
- Expectorants (Grade I recommendation) 1
- Postural drainage and chest percussion (Grade I recommendation) 1
3. Acute Exacerbation of Chronic Bronchitis
Defined as: Sudden clinical deterioration with increased sputum volume, purulence, and/or worsening shortness of breath 1
Recommended treatments:
- Short-acting β-agonists or anticholinergic bronchodilators (Grade A recommendation) 1
- Antibiotics, especially for severe exacerbations or those with severe airflow obstruction (Grade A recommendation) 1
- Short course (10-15 days) of systemic corticosteroids (Grade A recommendation) 1
NOT recommended for acute exacerbations:
- Theophylline (Grade D recommendation) 1
- Expectorants (Grade I recommendation) 1
- Postural drainage and chest percussion (Grade I recommendation) 1
Patient Communication Strategies
- Patient satisfaction depends more on physician-patient communication than receiving antibiotics 1
- Explain that antibiotics can increase risk of carrying antibiotic-resistant bacteria 1
- Inform patients about potential antibiotic side effects and rare but serious adverse reactions 1
- Use the term "chest cold" rather than "bronchitis" to reduce expectation for antibiotics 1
Special Considerations
- For suspected pertussis: perform diagnostic tests and initiate antibiotics to decrease pathogen shedding and disease spread 1
- For influenza: consider antiviral agents if within 48 hours of symptom onset 1
- In chronic bronchitis, studies specifically assessing effects of treatments on cough as an outcome are needed 1