What is the best management for tension headaches?

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Management of Tension Headache

For the treatment of tension-type headache, ibuprofen (400 mg) or acetaminophen (1000 mg) are recommended as first-line abortive therapies, while amitriptyline is suggested for prevention of chronic tension-type headache. 1

Abortive Treatment

First-line Medications

  • Ibuprofen 400 mg: Recommended as a first-line treatment with favorable efficacy and side-effect profile 1, 2
  • Acetaminophen 1000 mg: Equally effective for pain relief 1, 3

Important considerations:

  • Lower doses of acetaminophen (500-650 mg) have not shown statistically significant improvement 1
  • Both medications demonstrate statistically significant improvement in pain-free response at 2 hours 1
  • Ibuprofen may have a slightly faster onset of action, with greater pain reduction at 1 hour compared to other NSAIDs 3

Alternative NSAIDs

  • Naproxen 550-825 mg
  • Ketoprofen 50-75 mg 4

Caution: Using pain relievers more than twice weekly increases risk of progression to chronic daily headache 5

Preventive Treatment for Chronic Tension-Type Headache

First-line Prevention

  • Amitriptyline: Recommended for prevention of chronic tension-type headache 1
    • Effective doses: 50-100 mg daily
    • Significantly reduces monthly headache days 1

Important considerations:

  • Monitor for anticholinergic adverse effects, especially in:
    • Older patients
    • Patients with cardiac comorbidities
    • Risk of overdose 1

Treatments NOT Recommended

  • Botulinum toxin injections: Evidence shows no significant improvement in chronic tension-type headache outcomes 1
    • The VA/DoD Clinical Practice Guideline specifically recommends against botulinum/neurotoxin injection for chronic tension-type headache prevention 1

Non-pharmacological Approaches

Recommended Approaches

  • Physical therapy: Suggested for management of tension-type headache 1
  • Aerobic exercise or progressive strength training: Recommended for prevention 1

Other Approaches (Limited Evidence)

  • Relaxation therapies with EMG biofeedback (40-50% efficacy rate) 4
  • Cognitive therapy 5

Clinical Algorithm

  1. For acute tension headache episodes:

    • Start with ibuprofen 400 mg OR acetaminophen 1000 mg
    • Limit use to less than twice weekly to prevent medication overuse headache
  2. For patients with chronic tension-type headache (≥15 headache days/month for >3 months):

    • Consider amitriptyline starting at lower doses and titrating up to 50-100 mg daily
    • Add physical therapy or aerobic exercise program
  3. For inadequate response:

    • Consider combination of pharmacological and non-pharmacological approaches
    • Evaluate for medication overuse headache if frequent analgesic use
    • Consider referral to headache specialist if poor response to treatment

Common Pitfalls to Avoid

  • Using inadequate doses of acetaminophen (doses <1000 mg are less effective)
  • Prescribing botulinum toxin injections for tension-type headache (not recommended)
  • Failing to address medication overuse, which can perpetuate headaches
  • Neglecting non-pharmacological approaches, which can be effective adjuncts

By following this evidence-based approach, most patients with tension-type headache can achieve significant improvement in symptoms and quality of life.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Is any one analgesic superior for episodic tension-type headache?

The Journal of family practice, 2006

Research

[Treatment of tension headache].

Revue neurologique, 2000

Research

Tension-type headache.

American family physician, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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