What is the recommended treatment for a tension headache?

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Last updated: September 16, 2025View editorial policy

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Treatment of Tension Headache

For acute tension headache treatment, ibuprofen (400 mg) or acetaminophen (1000 mg) are recommended as first-line options. 1, 2

Acute Treatment Options

First-line Medications:

  • Ibuprofen 400 mg: Effective for short-term treatment of tension headache with significant improvement in pain-free response at 2 hours 1
  • Acetaminophen 1000 mg: Equally effective for short-term treatment 1
    • Important: Lower doses of acetaminophen (500-650 mg) do not show statistically significant improvement 1

Alternative Options:

  • Aspirin-acetaminophen-caffeine combination: Effective for mild to moderate headaches 2
    • Caution: Avoid in patients with peptic ulcer disease or bleeding disorders

Medication Administration Tips:

  • Take at the onset of headache
  • Take NSAIDs with food to minimize gastrointestinal side effects 2
  • Treat headaches as early as possible during an attack for improved efficacy 2

Preventive Treatment for Chronic Tension Headache

For patients with frequent tension headaches requiring preventive therapy:

  • Amitriptyline: Recommended for prevention of chronic tension-type headache (50-100 mg) 1
    • Both doses significantly reduce monthly headache days
    • Caution: Be aware of anticholinergic adverse effects, especially in older patients and those with cardiac comorbidities 1

Not Recommended:

  • Botulinum toxin injections: Evidence does not support use for chronic tension-type headache prevention 1

Non-Pharmacological Approaches

These approaches can complement medication therapy:

  • Maintain adequate hydration
  • Regular sleep schedule
  • Identify and avoid potential triggers
  • Stress reduction techniques 2
  • Physical therapy for tension-type headache 2
  • Aerobic exercise or progressive strength training 2

Important Limitations and Precautions

  • Limit medication use to prevent medication overuse headache:
    • NSAIDs: No more than 15 days per month 2
    • OTC medications: No more than 14 days per month 2

Treatment Algorithm

  1. Acute episode:

    • Start with ibuprofen 400 mg OR acetaminophen 1000 mg
    • If inadequate relief, consider aspirin-acetaminophen-caffeine combination
  2. For chronic/frequent tension headaches (occurring >15 days/month for >3 months):

    • Consider amitriptyline (starting at lower doses and titrating up to 50-100 mg)
    • Implement non-pharmacological approaches
  3. Follow-up:

    • Evaluate effectiveness after 4-6 weeks
    • Adjust treatment as needed 2
    • Allow 2-3 months for preventive medications to demonstrate full benefit 2

Common Pitfalls to Avoid

  • Using inadequate doses of acetaminophen (doses <1000 mg are not effective) 1
  • Overuse of acute medications leading to medication overuse headache
  • Failing to address lifestyle factors that may trigger headaches
  • Not allowing sufficient time for preventive medications to take effect
  • Ignoring comorbid conditions like anxiety and depression that may exacerbate headaches 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Headache Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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