Management of Pneumomediastinum
The management of pneumomediastinum should be primarily conservative with observation, rest, oxygen therapy, and pain control, as the condition is typically self-limiting and resolves spontaneously within a few days. 1
Diagnosis and Initial Assessment
Clinical presentation:
- Most common symptoms: central chest pain, dyspnea, voice distortion
- Physical findings: subcutaneous emphysema (face, neck, chest), "crunching" sound synchronized with heartbeat (Hamman's crunch)
- Symptoms typically resolve within 1-2 days after diagnosis 2
Diagnostic workup:
Management Algorithm
1. Assess Severity and Underlying Cause
Primary (spontaneous) pneumomediastinum:
- Usually occurs in young adults without apparent precipitating factors
- Common triggers: drug abuse (25%), asthma exacerbation, physical activity, violent coughing/vomiting 1
Secondary pneumomediastinum:
- Trauma-related
- Iatrogenic (post-procedural)
- Associated with underlying lung disease (e.g., COVID-19) 4
2. Conservative Management (First-Line)
Hospitalization considerations:
- Observation for 1-2 days if symptoms are mild and improving 2
- Longer hospitalization may be needed for patients with significant symptoms or underlying conditions
Supportive care:
- Rest and activity limitation
- Supplemental high-flow oxygen (10 L/min) to increase the rate of air reabsorption 5
- Adequate analgesia for pain control
- Avoid maneuvers that increase intrathoracic pressure (Valsalva, forceful coughing)
3. Special Considerations
For patients with underlying lung disease:
- More aggressive monitoring and management may be required
- Consider admission to a unit with respiratory expertise 5
For patients with associated pneumothorax:
Monitoring and Follow-up
During hospitalization:
- Monitor respiratory rate, oxygen saturation, heart rate, and blood pressure
- Watch for warning signs of deterioration: increasing dyspnea, expanding subcutaneous emphysema, hemodynamic instability 5
Discharge criteria:
- Resolution or significant improvement of symptoms
- No respiratory distress
- Stable vital signs
Long-term follow-up:
Special Situations
Tension Pneumomediastinum
- Rare but potentially life-threatening complication
- Presents with hemodynamic compromise similar to cardiac tamponade
- Requires immediate decompression
Pneumomediastinum with Mechanical Ventilation
- Ultra-protective lung ventilation strategies should be employed
- Consider ECMO in severe cases to facilitate lung-protective ventilation and prevent further barotrauma 6
Clinical Pearls
- Pneumomediastinum is typically self-limiting with excellent prognosis
- Inflammatory markers (WBC, CRP) may be mildly elevated but do not necessarily indicate infection 2
- Antibiotics are generally not required unless there is evidence of infection
- Avoid unnecessary invasive procedures which may prolong hospitalization without changing outcomes
- The tissues in the mediastinum will slowly reabsorb the air in the cavity 3
By following this approach, most cases of pneumomediastinum can be managed effectively with minimal intervention, allowing for natural resolution of the condition while monitoring for rare but serious complications.