What is the effect of Trimethylglycine (TMG) on hypertension?

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Last updated: March 4, 2025View editorial policy

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From the Research

Trimethylglycine (TMG) is not a recommended treatment for hypertension based on the provided evidence, and lifestyle modifications such as dietary changes, weight loss, and increased physical activity should be prioritized for blood pressure management. The effect of Trimethylglycine (TMG) on hypertension is not directly addressed in the provided studies, which focus on lifestyle modifications and non-pharmacological interventions for blood pressure management 1, 2, 3, 4, 5. Key findings from the studies include:

  • Lifestyle modifications such as weight loss, increased physical activity, and dietary changes can lower blood pressure and reduce the risk of hypertension 1, 3, 4
  • The Dietary Approach to Stop Hypertension (DASH) diet is a effective intervention for lowering blood pressure 4
  • Non-pharmacological interventions such as aerobic exercise, isometric training, and low-sodium and high-potassium salt can also lower blood pressure 4 While TMG may have potential benefits for cardiovascular health, the current evidence does not support its use as a treatment for hypertension, and patients should focus on established lifestyle modifications and consult with their healthcare provider before starting any new supplements. It is essential to prioritize lifestyle modifications and non-pharmacological interventions that have been shown to be effective in managing hypertension, rather than relying on unproven supplements like TMG 2, 5.

References

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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