What precautions are needed for active Herpes Zoster (shingles)?

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Last updated: February 8, 2025View editorial policy

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From the Guidelines

Active Herpes Zoster (shingles) requires standard infection-control precautions, and in cases of disseminated zoster or immunocompromised patients, airborne and contact precautions are necessary.

Precautions for Active Herpes Zoster

  • Standard infection-control precautions should be followed in all cases of herpes zoster infection 1
  • Airborne and contact precautions are needed when disseminated zoster (defined as “appearance of lesions in >3 dermatomes”) is suspected or the patient is immunocompromised 1
  • Covering of lesions is recommended for immunocompetent persons with localized Herpes Zoster, and they should be restricted from caring for high-risk patients until all lesions dry and crust 1
  • Exclude from duty until all lesions dry and crust for healthcare personnel with disseminated or localized Herpes Zoster in immunocompromised persons, or those without evidence of varicella immunity 1
  • Antiviral agents have been shown to decrease viral shedding and lower the duration of herpes zoster lesions 1

Vaccination

  • Recombinant zoster vaccine (RZV) is recommended for the prevention of herpes zoster and related complications for immunocompetent adults aged 50 years or older 1

From the Research

Precautions for Active Herpes Zoster (Shingles)

To manage and prevent the complications of herpes zoster, several precautions can be taken:

  • Vaccination is essential for the prevention of herpes zoster and its consequences, as stated in 2
  • The zoster vaccine is recommended for most people older than 60, and reduces the incidence of herpes zoster and the occurrence of post-herpetic neuralgia, according to 3
  • A new recombinant subunit vaccine, HZ/su (Shingrix®), has demonstrated an overall vaccine efficacy of 97.2% among participants 50 years of age or older, indicating a significantly reduced risk of HZ in these individuals, as reported in 4
  • Patient history is critical in reaching a diagnosis, not only to manage the outbreak effectively, but also to prevent severe complications such as dissemination of the virus into the central nervous system, as mentioned in 5
  • Antiviral agents and pain management are currently used in HZ therapy, as stated in 4
  • Practical, evidence-based recommendations for the management of acute shingles (herpes zoster) have been published, including guidelines for the use of antiviral agents and pain management, as summarized in 6

High-Risk Groups

Certain groups are at higher risk for developing herpes zoster and its complications, including:

  • Immunocompetent individuals aged at least 50 years, who are at risk for developing HZ due to the decline in cell-mediated immunity, as stated in 2
  • Immunocompetent individuals older than 60 years, who are at higher risk for post-herpetic neuralgia, as reported in 3
  • Immunocompromised patients, who are at particularly high risk for herpes zoster, as mentioned in 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Shedding Light on Shingles: The Power of Prevention.

The American journal of medicine, 2016

Research

Herpes zoster.

The Medical clinics of North America, 2013

Research

Shingrix for Herpes Zoster: A Review.

Skin therapy letter, 2019

Research

Herpes zoster: A primary care approach to diagnosis and treatment.

JAAPA : official journal of the American Academy of Physician Assistants, 2022

Research

Management of acute shingles (herpes zoster).

Reviews in neurological diseases, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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