From the Research
Taking lisinopril in the evening is as effective as taking it in the morning, and patients can be advised to take their regular antihypertensive medications at a convenient time that minimizes any undesirable effects. The standard dosage of lisinopril typically starts at 10mg once daily, which can be adjusted by your doctor based on your blood pressure response. Lisinopril has a long duration of action (24 hours) which allows for once-daily dosing, and its administration can help maintain consistent blood pressure control throughout the day.
Key Considerations
- The TIME study, a prospective, randomised, open-label, blinded-endpoint clinical trial published in 2022 in the Lancet, found that evening dosing of usual antihypertensive medication was not different from morning dosing in terms of major cardiovascular outcomes 1.
- It's essential to take lisinopril consistently at the same time each day to maintain steady blood levels.
- If you experience dizziness when standing up quickly, ensure adequate hydration and rise slowly from sitting or lying positions.
- You should monitor your blood pressure regularly and keep a log to share with your doctor, who may adjust your dosage or timing if your morning and evening readings remain elevated.
- Lifestyle modifications like reducing sodium intake, regular exercise, and stress management are also crucial components of blood pressure management alongside medication.
Administration Timing
- The study found that patients can take their antihypertensive medications at a convenient time, and there is no significant difference in major cardiovascular outcomes between evening and morning dosing 1.
- However, it's crucial to consider individual patient factors, such as lifestyle and potential side effects, when determining the optimal timing for taking lisinopril.
Monitoring and Adjustments
- Regular blood pressure monitoring is vital to assess the effectiveness of lisinopril and make any necessary adjustments to the dosage or timing.
- Patients should keep a log of their blood pressure readings to share with their doctor, who can use this information to make informed decisions about their treatment plan.