What is the absolute contraindication to peritoneal dialysis (PD)?

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Last updated: February 8, 2025View editorial policy

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From the Guidelines

Documented loss of peritoneal function is the absolute contraindication to peritoneal dialysis (PD).

Key Contraindications

  • Documented loss of peritoneal function or extensive abdominal adhesions that limit dialysate flow
  • In the absence of a suitable assistant, a patient who is physically or mentally incapable of performing PD
  • Uncorrectable mechanical defects that prevent effective PD or increase the risk of infection as stated in the guidelines by the American Journal of Kidney Diseases 1. The rationale behind this is that PD efficiency relies on effective peritoneal blood flow, dialysate flow, sufficient peritoneal surface area, and permeability to allow adequate solute and fluid removal. Any compromise in these functions may result in inadequate peritoneal dialysis and thus the failure of PD, as explained in the study 1.

From the Research

Absolute Contraindications to Peritoneal Dialysis (PD)

  • Recent abdominal or cardiothoracic surgery 2
  • Diaphragmatic peritoneal-pleural connections 2
  • Faecal or fungal peritonitis 2

Relative Contraindications to Peritoneal Dialysis (PD)

  • High age 3
  • Comorbidities such as diabetes mellitus, obesity, polycystic kidney disease, heart failure 3
  • Previous history of abdominal surgery and renal allograft failure 3
  • Presence of a ventriculoperitoneal shunt (VPS) is not an absolute contraindication, but requires careful consideration 4

Special Considerations

  • Patients with spina bifida and/or VPS can be considered for PD, but require close monitoring and individualized care 4
  • Percutaneous endoscopic gastrostomy (PEG) tube placement in adult PD patients is not absolutely contraindicated, but requires careful consideration and management 5

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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