Types of Hypovolemic Shock
Hypovolemic shock is classified into four major categories based on the source of volume loss: hemorrhagic, non-hemorrhagic external fluid loss, third-space losses, and traumatic shock. 1
Classification of Hypovolemic Shock Types
1. Hemorrhagic Shock
- Caused by acute blood loss from:
- Gastrointestinal bleeding
- Trauma with external or internal bleeding
- Obstetric/gynecological bleeding
- Ruptured aneurysms
- Surgical complications
2. Non-Hemorrhagic External Fluid Loss
- Results from excessive loss of body fluids:
- Severe vomiting or diarrhea
- Excessive sweating
- Burns with plasma loss
- Diabetic ketoacidosis with polyuria
- Inadequate fluid intake
3. Third-Space Losses
- Fluid shifts from intravascular to interstitial space:
- Peritonitis
- Pancreatitis
- Intestinal obstruction
- Severe sepsis with capillary leak
- Post-surgical fluid sequestration
4. Traumatic Shock
- Combined mechanisms including:
- Blood loss
- Tissue damage
- Inflammatory responses
- Potential neurogenic components
Pathophysiologic Features
Hypovolemic shock is characterized by a critical decrease in intravascular volume resulting in:
- Diminished venous return (preload)
- Decreased ventricular filling
- Reduced stroke volume
- Decreased cardiac output
- Tissue hypoperfusion and cellular hypoxia 2, 3
Diagnostic Features
Echocardiographic Findings
- Small hyperdynamic unloaded ventricle
- Reduced left ventricular end-diastolic area
- Small inferior vena cava diameter (<10 mm) with inspiratory collapse in spontaneously breathing patients
- In mechanically ventilated patients: small IVC diameter at end expiration with variable respiratory changes 2
Clinical Presentation (Progressive Stages)
Compensated shock:
- Tachycardia
- Normal blood pressure
- Preserved mental status
- Mild peripheral vasoconstriction
Decompensated shock:
- Persistent tachycardia
- Hypotension
- Altered mental status
- Poor peripheral perfusion
- Decreased urine output
Irreversible shock:
- End-organ damage
- Metabolic acidosis
- Multiple organ dysfunction
Management Principles
Initial Resuscitation
- Administer isotonic crystalloids (preferably balanced/buffered solutions)
- For adults: Boluses titrated to clinical response
- For children: 10-20 mL/kg boluses over 5-10 minutes, up to 40-60 mL/kg in first hour 2, 4
- Monitor for signs of fluid overload (hepatomegaly, rales)
- Consider blood products for hemorrhagic shock 4
Special Considerations
- In children with severe hemolytic anemia who are not hypotensive, blood transfusion is superior to crystalloid or albumin bolusing 2
- In resource-limited settings without ICU availability, limit fluid boluses to 40 mL/kg in the first hour if hypotension is present 4
Monitoring Response
- Clinical markers: Heart rate, blood pressure, capillary refill, level of consciousness, urine output
- Advanced hemodynamic variables when available: Cardiac output/index, systemic vascular resistance, central venous oxygen saturation
- Trends in blood lactate levels 4
Common Pitfalls
- Relying solely on blood pressure as an endpoint for resuscitation
- Delayed recognition of fluid overload
- Inappropriate fluid choice
- Inadequate monitoring
- Failure to consider specific disease states 4
Early recognition and prompt, appropriate fluid resuscitation are critical to preventing progression to irreversible shock and multi-organ failure.