Is infectious mononucleosis (mono) neck swelling typically unilateral or bilateral?

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From the Research

Clinical Presentation of Infectious Mononucleosis

  • The clinical presentation of infectious mononucleosis typically includes fever, pharyngitis, and cervical lymphadenopathy 1, 2.
  • Cervical lymph node enlargement is a characteristic feature of the disease, but the studies do not specifically mention whether it is typically unilateral or bilateral 1, 2.
  • However, one study mentions "bilateral posterior cervical adenopathy" as a characteristic clinical feature of Epstein-Barr virus (EBV) infectious mononucleosis 3.
  • Another study reports a case of infectious mononucleosis complicated with bilateral peritonsillar abscess, suggesting that bilateral neck swelling can occur in some cases 4.

Lymph Node Enlargement in Infectious Mononucleosis

  • Lymph node enlargement in infectious mononucleosis can be severe, and may be the primary presenting symptom in some cases 5.
  • The studies do not provide a clear answer to whether neck swelling in infectious mononucleosis is typically unilateral or bilateral, but suggest that bilateral lymph node enlargement can occur 3, 4.

References

Research

Infectious mononucleosis.

Clinical & translational immunology, 2015

Research

Infectious mononucleosis.

Primary care update for Ob/Gyns, 2001

Research

[The neck cysts and infectious mononucleosis due to cytomegalovirus].

Anales otorrinolaringologicos ibero-americanos, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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