Treatment of Jellyfish Stings
The first-line treatment for jellyfish stings is to rinse with seawater, apply vinegar (4-6% acetic acid) for at least 30 seconds to inactivate nematocysts, then immerse the affected area in hot water (40°C/104°F) for 20-30 minutes for pain relief. 1
Initial Management
Safety and Tentacle Removal
Nematocyst Inactivation
- Apply vinegar (4-6% acetic acid solution) liberally for at least 30 seconds 2, 1
- If vinegar is unavailable, use a baking soda slurry as an alternative 2
- AVOID using fresh water, alcohol, methylated spirits, or scraping the area, as these can trigger additional nematocyst discharge 1, 3
- AVOID pressure immobilization bandages as they may cause further venom release 2, 3
Pain Management
First Choice: Hot Water Immersion
Alternative Options (if hot water is unavailable)
Ineffective or Harmful Treatments to AVOID
Monitoring for Complications
- Monitor for systemic reactions requiring emergency medical services 1:
- Difficulty breathing
- Signs of shock
- Severe or persistent pain
- Widespread rash or swelling
Important Considerations and Caveats
The quality of evidence for jellyfish sting treatments is generally low, with significant heterogeneity across studies 6
In severe cases involving dangerous species (like box jellyfish), stabilizing vital functions takes priority 3
For prevention of scarring, monitor for infection and manage hypertrophic scarring according to general wound care principles 1
The treatment approach outlined above follows the most recent guidelines from the American Heart Association and American Red Cross, which provide the strongest evidence for jellyfish sting management 1.