What is the treatment for jellyfish stings?

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Last updated: August 11, 2025View editorial policy

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Treatment of Jellyfish Stings

The first-line treatment for jellyfish stings is to rinse with seawater, apply vinegar (4-6% acetic acid) for at least 30 seconds to inactivate nematocysts, then immerse the affected area in hot water (40°C/104°F) for 20-30 minutes for pain relief. 1

Initial Management

  1. Safety and Tentacle Removal

    • Remove the victim from the water to prevent further stings
    • Remove any remaining tentacles by carefully lifting or pulling them while avoiding direct skin contact 1
    • Do NOT use bare hands - use tweezers, gloves, or another object
    • Do NOT scrape the area as this can cause additional venom release 1
  2. Nematocyst Inactivation

    • Apply vinegar (4-6% acetic acid solution) liberally for at least 30 seconds 2, 1
    • If vinegar is unavailable, use a baking soda slurry as an alternative 2
    • AVOID using fresh water, alcohol, methylated spirits, or scraping the area, as these can trigger additional nematocyst discharge 1, 3
    • AVOID pressure immobilization bandages as they may cause further venom release 2, 3

Pain Management

  1. First Choice: Hot Water Immersion

    • Immerse the affected area in hot water (as hot as tolerated or approximately 40°C/104°F) for 20-30 minutes or until pain subsides 2, 1
    • This method has the strongest evidence for pain relief 1
  2. Alternative Options (if hot water is unavailable)

    • Apply topical lidocaine cream or gel (4-5% or 10-15% formulations) 1
    • Use dry hot packs 2, 1
    • As a last resort, apply dry cold packs (less effective) 2, 1
  3. Ineffective or Harmful Treatments to AVOID

    • Meat tenderizer 1
    • Aluminum sulfate 2
    • Urine (folk remedy with no scientific support) 1
    • Alcohol or methylated spirits 1, 3

Monitoring for Complications

  • Monitor for systemic reactions requiring emergency medical services 1:
    • Difficulty breathing
    • Signs of shock
    • Severe or persistent pain
    • Widespread rash or swelling

Important Considerations and Caveats

  • Treatment efficacy varies by jellyfish species 1, 4

    • The guidelines above are most applicable to North American jellyfish species 1
    • For Physalia species (bluebottles/Portuguese man-of-war), vinegar may actually increase envenomation and should be avoided 5
  • The quality of evidence for jellyfish sting treatments is generally low, with significant heterogeneity across studies 6

  • In severe cases involving dangerous species (like box jellyfish), stabilizing vital functions takes priority 3

  • For prevention of scarring, monitor for infection and manage hypertrophic scarring according to general wound care principles 1

The treatment approach outlined above follows the most recent guidelines from the American Heart Association and American Red Cross, which provide the strongest evidence for jellyfish sting management 1.

References

Guideline

Jellyfish Sting Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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