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Differential Diagnosis for 10-year-old with Toenails Falling Off

  • Single most likely diagnosis:
    • Onychomycosis (fungal infection of the nail) - This is a common condition in children that can cause toenails to fall off due to fungal infection.
  • Other Likely diagnoses:
    • Trauma - Repeated trauma to the toenails, such as from sports or tight shoes, can cause the nails to fall off.
    • Psoriasis - A skin condition that can cause nail changes, including thickening, pitting, and nail loss.
    • Eczema (atopic dermatitis) - Can cause nail changes and nail loss, especially if the eczema is severe.
    • Nutritional deficiencies (e.g., iron, zinc, biotin) - Deficiencies in certain nutrients can affect nail health and lead to nail loss.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Autoimmune disorders (e.g., alopecia areata, lupus) - Although less common, these conditions can cause nail loss and have significant systemic implications if left untreated.
    • Thyroid disorders - Both hypothyroidism and hyperthyroidism can cause nail changes, including nail loss.
    • Diabetes - Can cause nail changes and nail loss due to nerve damage and poor circulation.
  • Rare diagnoses:
    • Lichen planus - A rare skin condition that can cause nail changes and nail loss.
    • Nail patella syndrome - A rare genetic disorder that affects the development of nails and other parts of the body.
    • Epidermolysis bullosa - A rare genetic disorder that causes blistering of the skin and can lead to nail loss.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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