What precautions should caregivers take to prevent the spread of Methicillin-resistant Staphylococcus aureus (MRSA)?

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Last updated: August 12, 2025View editorial policy

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Caregiver Precautions for MRSA

Healthcare workers and caregivers must implement strict hand hygiene, wear gloves and gowns when caring for MRSA-infected or colonized patients, and ensure proper environmental cleaning with appropriate disinfectants to prevent MRSA transmission.

Hand Hygiene - The Foundation of MRSA Prevention

Hand hygiene is the single most important method for preventing MRSA transmission:

  • Preferred method: Use alcohol-based hand rubs when hands are not visibly soiled 1

    • More effective at removing organisms
    • Requires less time
    • Causes less skin irritation than soap and water
    • Increases compliance with hand hygiene protocols
  • When to perform hand hygiene:

    • Before and after each patient contact
    • After removing gloves
    • Between dirty and clean procedures on the same patient
    • After contact with potentially contaminated surfaces or equipment 1
  • Technique:

    • Apply enough product to cover all hand surfaces
    • Rub hands together until dry
    • For visibly soiled hands, wash with soap and water 1

Personal Protective Equipment (PPE)

  1. Gloves:

    • Wear clean, non-sterile gloves when entering the room of a MRSA-infected or colonized patient 1
    • Change gloves after contact with material containing high concentrations of MRSA (e.g., wound drainage, stool) 1
    • Remove gloves before leaving the patient's room 1
    • Never wash or reuse gloves 1
  2. Gowns:

    • Wear a clean, non-sterile gown when entering the room if:
      • Substantial contact with the patient is anticipated
      • Contact with environmental surfaces in the patient's room is likely
      • The patient is incontinent or has uncontained drainage 1
    • Remove gown before leaving the patient's room 1
    • Change immediately if visibly soiled or penetrated by blood/body fluids 1
  3. Proper Sequence for Removing PPE:

    • Remove gloves first
    • Perform hand hygiene immediately after glove removal
    • Remove gown
    • Perform hand hygiene again 1

Patient Placement and Isolation

  • Place MRSA-infected or colonized patients in private rooms when possible 1
  • If private rooms are unavailable, cohort MRSA patients together 1
  • Implement contact precautions for all encounters with MRSA-colonized patients 1
  • Ensure proper communication about MRSA status when transferring patients to other facilities 1

Environmental Cleaning and Disinfection

  • Pay close attention to high-touch surfaces in patient care areas:

    • Bed rails
    • Bedside commodes
    • Doorknobs
    • Faucet handles
    • Medical equipment 1
  • Use EPA-registered disinfectants appropriate for the surface 1

  • Ensure compliance with cleaning and disinfection procedures by housekeeping staff 1

  • Consider using dedicated equipment for MRSA patients:

    • Stethoscopes
    • Blood pressure cuffs
    • Thermometers 1
  • If equipment must be shared, thoroughly clean and disinfect between patients 1

Special Considerations

  • Artificial nails: Do not wear artificial fingernails when caring for high-risk patients 1
  • Jewelry: Avoid hand or nail jewelry that makes glove use difficult or compromises glove integrity 1
  • Duration of precautions: MRSA colonization can persist indefinitely; consider multiple negative cultures (at least three consecutive negative results from multiple body sites) before discontinuing precautions 1

Common Pitfalls to Avoid

  1. Inadequate hand hygiene: The most common cause of healthcare-associated infections 1
  2. Improper glove removal: Can lead to hand contamination even with glove use 2
  3. Premature discontinuation of contact precautions: MRSA colonization can persist for extended periods 1
  4. Neglecting environmental cleaning: MRSA can survive on environmental surfaces 1
  5. Inconsistent adherence to protocols: Regular education and monitoring of compliance is essential 1

By consistently implementing these precautions, caregivers can significantly reduce the risk of MRSA transmission in healthcare settings and protect both patients and themselves from infection.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Safe removal of gloves from contact precautions: The role of hand hygiene.

American journal of infection control, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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