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Differential Diagnosis for a 65-year-old Male with Urinary Retention

Single Most Likely Diagnosis

  • Benign Prostatic Hyperplasia (BPH): This is the most common cause of urinary retention in older men. The enlarged prostate gland can compress the urethra, leading to obstruction of urine flow.

Other Likely Diagnoses

  • Urinary Tract Infection (UTI): UTIs can cause urinary retention, especially in older adults, due to inflammation and irritation of the bladder and urethra.
  • Neurogenic Bladder: Conditions such as diabetes, stroke, or spinal cord injury can damage the nerves that control bladder function, leading to urinary retention.
  • Medication Side Effects: Certain medications, such as anticholinergics, antihistamines, and decongestants, can cause urinary retention as a side effect.
  • Constipation: Severe constipation can put pressure on the urethra, leading to urinary retention.

Do Not Miss Diagnoses

  • Spinal Cord Compression: Cauda equina syndrome or spinal cord compression can cause sudden onset of urinary retention and is a medical emergency.
  • Bladder Outlet Obstruction: Obstruction due to bladder stones, blood clots, or tumors can cause urinary retention and requires prompt attention.
  • Acute Kidney Injury: Urinary retention can lead to acute kidney injury if not promptly relieved, making it essential to address the underlying cause.

Rare Diagnoses

  • Prostate Cancer: Although less common than BPH, prostate cancer can also cause urinary retention due to obstruction of the urethra.
  • Urethral Stricture: Narrowing of the urethra due to injury, infection, or inflammation can cause urinary retention.
  • Bladder Neck Contracture: Scarring at the bladder neck can cause obstruction and urinary retention.
  • Neurological Disorders: Conditions such as multiple sclerosis, Parkinson's disease, or peripheral neuropathy can affect bladder function and cause urinary retention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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